Wise, dedicated, passionate and competitive--all words that accurately describe Merrill Goozner who in 2012 raised the bar for healthcare journalism when he took over the helm at Modern Healthcare.
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Analyzing the relationship between gene expression and phenotype in space-flown mice using a causal inference machine learning ensemble.
Sci Rep
January 2025
NASA Ames Research Center, Moffett Field, Mountain View, USA.
Spaceflight has several detrimental effects on human and rodent health. For example, liver dysfunction is a common phenotype observed in space-flown rodents, and this dysfunction is partially reflected in transcriptomic changes. Studies linking transcriptomics with liver dysfunction rely on tools which exploit correlation, but these tools make no attempt to disambiguate true correlations from spurious ones.
View Article and Find Full Text PDFA prospective observational study of operating room traffic during shunt surgery: who comes in and why?
J Neurosurg Pediatr
November 2024
2Department of Neurosurgery, University of Tennessee Health Science Center, Memphis.
Objective: Shunt infections are costly and stressful for families, patients, and providers. Many institutions use shunt checklists in an effort to reduce the risk of infection following shunt surgery. Such protocols often aim to limit operating room (OR) foot traffic, but there is little evidence that supports the theory that greater OR traffic increases the risk of acquiring a shunt infection through contamination of the air.
View Article and Find Full Text PDFAAPM task group report 314: Fault recovery in external beam radiation therapy.
Med Phys
January 2025
Sun Nuclear, Melbourne, Florida, USA.
Task Group (TG) 314 of the American Association of Physicists in Medicine (AAPM) was charged to develop guidance for recovering from fault states in radiation therapy, specifically regarding the delivery of photon or electron beams using a linear accelerator (linac) including ancillary systems. The fault conditions addressed may involve software, hardware, or a combination of causes. The report provides detailed recommendations for the proactive steps to be taken before a fault, the actions to be taken at the time of a fault, and the safety steps before returning a linac to clinical service, as well as the activities that device manufacturers and standard organizations can do to prevent and resolve the faults.
View Article and Find Full Text PDFRealizing one-dimensional moiré chains with strong electron localization in two-dimensional twisted bilayer WSe.
Proc Natl Acad Sci U S A
November 2024
Center for Advanced Quantum Studies, School of Physics and Astronomy, Beijing Normal University, Beijing 100875, China.
Two-dimensional (2D) moiré systems based on twisted bilayer graphene and transition metal dichalcogenides provide a promising platform to investigate emergent phenomena driven by strong electron-electron interactions in partially filled flat bands. A natural question arises: Is it possible to expand the 2D correlated moiré physics to one-dimensional (1D) that electron-electron correlation is expected to be further enhanced? This requires selectively doping of 1D moiré chain, which seems to be not within the grasp of today's technology. Therefore, an experimental demonstration of the 1D moiré chain with partially filled electronic states remains absent.
View Article and Find Full Text PDFDynamic flexoelectric instabilities in nematic liquid crystals.
Phys Rev E
August 2024
Landau Institute for Theoretical Physics, RAS, 142432, Chernogolovka, Moscow region, Russia.
Electrohydrodynamic phenomena in liquid crystals constitute an old but still very active research area. The reason is that these phenomena play the key role in various applications of liquid crystals and due to the general interest of the physical community in out-of-equilibrium systems. Nematic liquid crystals (NLCs) are ideally representative for such investigations.
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