Observational pilot study of patients with carpal tunnel syndrome treated with Nucleo CMP Forte™.

Aim: Carpal tunnel syndrome (CTS) is a very common entrapment neuropathy characterized by pain and paresthesia in the territory of the median nerve. Although this syndrome has a considerable impact on the patient's quality of life, its medical treatment is far from optimal.

Material & Methods: We performed an observational study to evaluate Nucleo CMP Forte in patients with electromyography-confirmed, mild-moderate CTS. Pain was assessed using a visual analog scale, electromyogram and the SF-36.

Results: Pain decreased significantly after 6 months. Quality of life improved significantly in the pain dimensions. No significant differences were observed in electromyographic findings. No adverse events were reported.

Conclusions: Nucleotides could prove useful for the nonsurgical treatment of CTS. Further studies are necessary to confirm this.