AI Article Synopsis
- Chronic HCV infection is linked to cardiovascular diseases and higher cardiovascular mortality, but the exact mechanisms behind this connection are not fully understood.
- The review assesses HCV as a non-traditional risk factor for cardiovascular disease, exploring the role of systemic inflammation and metabolic issues.
- It also provides practical guidance for assessing cardiovascular risk in patients with chronic hepatitis C and emphasizes the need for increased awareness among healthcare specialists about treatment options.
Article Abstract
Extrahepatic manifestations of chronic HCV infection include cardiovascular diseases and an increase in cardiovascular mortality. The pathogenic mechanisms by which HCV contributes to cardiovascular disease are not well defined, however, it is likely that systemic inflammation, and the promotion of other metabolic diseases are involved. In this Review, the evidence for HCV infection as a non-traditional risk factor for cardiovascular disease is evaluated. Furthermore, practical advice to evaluate cardiovascular disease risk and disease in chronic hepatitis C patients are included for help in daily clinical practice. Despite the advances in therapies for the treatment of HCV, there remains a need for increased awareness among specialists so that patients are more likely to obtain the treatment required to mitigate disease progression.
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| http://dx.doi.org/10.3851/IMP3248 | DOI Listing |
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