AI Article Synopsis
- Neurological issues related to HCV infection, such as fatigue, depression, and cognitive problems, are often overlooked in clinical settings.
- Evidence suggests a potential link between HCV and an increased risk of developing Parkinson's disease, though the exact mechanisms are still unclear.
- Treatment for HCV has shown to improve neuropsychiatric symptoms, leading to a better overall quality of life for patients.
Article Abstract
Neurological manifestations of HCV infection appear to be under-recognized in clinical practice despite the majority of HCV-infected patients experiencing symptoms such as fatigue, depression and cognitive dysfunction. There is also growing evidence for a link between HCV infection and an increased risk of Parkinson's disease. The mechanism underpinning the association between HCV and these neuropsychiatric syndromes still requires further investigation. Here we review the pre-clinical and clinical evidence for a link between HCV and effects on the central nervous system leading to neuropsychiatric syndromes. Lastly, we describe how improvements in neuropsychiatric manifestations of HCV following treatment have been observed, which is subsequently reflected in an overall improvement in health-related quality of life.
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| http://dx.doi.org/10.3851/IMP3245 | DOI Listing |
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