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Aim: To compare the clinical performance of 4 spectral-domain (SD) optical coherence tomography angiography (OCTA) systems: AngioVue™, AngioPlex™, Spectralis OCTA, AngioScan, and 1 swept-source (SS) OCTA SS OCT Angio™.
Methods: Twenty-seven undilated right eyes of 27 participants underwent OCTA examination using five different systems respectively for both 3×3 and 6×6 mm scan pattern (Spectralis OCTA for 3×3 mm scan only). Image quality, including vessel valid visibility and the number of motion artifacts, and acquisition time were evaluated. Repeated measures analysis of variance (ANOVA) with Bonferroni's post-test and Friedman test with Dunn's post-test were used to compare measurements.
Results: The age of the subjects was 28.19±5.55y (range, 23-49y). The spherical equivalent refraction was -2.55±1.84 D (range, 0.00 to -5.25 D). Significant difference was observed in the evaluation of vessel valid visibility (AngioVue the highest: 0.111±0.031 for 3×3 mm scan and 0.128±0.020 for 6×6 mm scan), number of motion artifacts (AngioVue the fewest: 0.778±1.086 for 3×3 mm scan and 0.333±0.620 for 6×6 mm scan) and acquisition time (AngioPlex the shortest: 8.537±1.921s for 3×3 mm scan and 8.298±1.741s for 6×6 mm scan; all <0.001).
Conclusion: There is poor agreement of measurements among systems. AngioVue provides images with the highest vessel valid visibility and the fewest motion artifacts. AngioPlex achieves the shortest acquisition.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232334 | PMC |
| http://dx.doi.org/10.18240/ijo.2018.11.09 | DOI Listing |
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