Aim: To measure the parameters of endothelium in the central and peripheral parts of the cornea and evaluate the influence of wearing the hard and soft contact lenses on the mentioned parameters.
Methods: A specular microscope was used to measure the corneal endothelium parameters in both eyes of 139 Caucasians (a total of 278). All participants were divided into three groups: soft lens wearers, hard lens wearers and a control group. Factors, such as age, smoking, types of lens material, duration of lens wear and lens air permeability were assessed to determine their impact on the morphometric parameters of the endothelium.
Results: A lower percentage of hexagon-like cells and higher cell variation than in other groups were determined in hard contact lens wearers. The difference in density of endotheliocytes between the groups was not observed. The measurements of the morphometric parameters in soft contact lens wearers did not depend neither on the duration of lens wear, nor on air permeability. The relation between the patients' age and the variation of endothelium parameters was determined in the group of hard contact lens wearers.
Conclusion: Wearing hard contact lenses provokes pleomorphism and polymegethism of the corneal endothelium, while soft contact lenses do not impact any parameters of the endothelium, most likely due to higher air permeability.
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http://dx.doi.org/10.18240/ijo.2018.11.06 | DOI Listing |
Ophthalmologie
January 2025
Klinik für Augenheilkunde, Klinikum Chemnitz, Flemmingstr. 2, 09116, Chemnitz, Deutschland.
Background: Damage induced by ultraviolet (UV) radiation plays a decisive role in the carcinogenesis of malignant tumors of the eyelids.
Methods: A selective literature search was performed in PubMed and Google Scholar.
Results: Large epidemiological studies show an increase in the prevalence of eyelid tumors in recent decades.
Cornea
January 2025
Department of Ophthalmology, Rothschild Foundation, Paris, France; and.
Purpose: The purpose of this study was to investigate the effect of hypoxia and hypobaric conditions on refraction and central corneal thickness on healthy corneas during an ascent without oxygen supplementation above 7000 m (23 000 ft).
Methods: Twelve multinational mountaineers were included in a prospective observational cohort study during an expedition to the Korzhenevskoi Peak (7105 m). The two patients excluded from the study had a history with keratoconus or were current wearers of rigid contact lenses.
Clin Exp Optom
January 2025
Eurolens Research, Division of Pharmacy and Optometry, The University of Manchester, Manchester, UK.
Clinical Relevance: Knowledge of contact lens prescribing trends can (a) assist practitioners to benchmark their own prescribing habits, (b) help the contact lens industry understand preferred products, and (c) support academics in scholarly writings.
Background: This work aims to document contact lens prescribing trends in Australia over the past quarter of a century.
Methods: An annual survey of contact lens prescribing trends was conducted in Australia each year from 2000 to 2024, inclusive, by asking optometrists to provide information relating to 10 consecutive contact lens fits undertaken between January and March.
J Control Release
January 2025
Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Cixi Biomedical Research Institute, School of Pharmaceutical Sciences, Wenzhou Medical University, Ningbo, China. Electronic address:
Severe corneal injuries can cause visual impairment even blindness. Surgically stitching or implanting biomaterials have been developed, but their implementation requires professional surgeons, failing to address the immediate need of medical treatment. The pressing challenge lies in developing multifunctional biomaterials that enable self-management of corneal injuries.
View Article and Find Full Text PDFAm J Ophthalmol
January 2025
Department of Ophthalmology, University of Warmia and Mazury, Olsztyn, Poland; Institute for Research in Ophthalmology, Foundation for Ophthalmology Development, Poznan Poland. Electronic address:
Purpose: Treatment of myopia has been informed by more than 3 decades of clinical trials and other observations. However, controversies regarding myopia control remain, such as when to stop treatment and what is the long-term efficacy of treatment. This perspective aims to describe clinically relevant and current controversies regarding myopia treatment.
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