AI Article Synopsis
- A 53-year-old woman with severe chronic inflammatory demyelinating polyneuropathy (CIDP) experienced progressive paralysis and respiratory failure despite standard treatments.
- After switching to high-dose intravenous immunoglobulin therapy (IVIg), her muscle weakness showed gradual improvement.
- This case suggests that patients with refractory CIDP might benefit from high-dose IVIg, even if standard treatments fail.
Article Abstract
We report the case of a 53-year-old woman with severe chronic inflammatory demyelinating polyneuropathy (CIDP) who developed progressive tetraplegia with respiratory failure despite receiving a standard dose of intravenous immunoglobulin therapy (IVIg), steroid pulse therapy, plasma exchange, and cyclosporine. We administered high-dose IVIg (3 g/kg; 0.6 g/kg/day for 5 consecutive days at monthly intervals). The patient's muscle weakness gradually improved after IVIg. She recovered completely 2 years after the onset of symptoms. The effects of IVIg treatment in individuals with CIDP may vary in each patient. In patients with refractory CIDP receiving standard-dose IVIg, repeated high-dose IVIg treatment can be considered.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465009 | PMC |
| http://dx.doi.org/10.2169/internalmedicine.1723-18 | DOI Listing |
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