Outcomes following laparoscopic Roux-en-Y gastric bypass (LRYGB) vary by sex: Analysis of 83,059 women and men with morbid obesity.

Am J Surg

Department of Surgery, Inspira Health Network, 1505 West Sherman Avenue, Vineland, NJ, USA. Electronic address:

Published: June 2019

Background: Previously we have reported variation in pre-operative clinical characteristics between women and men undergoing laparoscopic roux-en-Y gastric bypass (LRYGB). However, variation by sex in post-operative outcomes following LRYGB has not been investigated.

Methods: Pre-operative data was compared to follow-up data at 12 months after surgery on 83,059 patients from the Surgical Review Corporation's BOLD database. Data included age, weight, BMI, and 31 obesity-related medical conditions.

Results: Men had increased weight, actual weight lost, and BMI. Women had higher rates of gastrointestinal and mental health disorders. Men failed to resolve cardiopulmonary/vascular and metabolic derangements, abdominal hernia, and were more functionally impaired than women.

Conclusions: Overall, women may benefit more from LRYG than men, as their pre-operative conditions showed greater improvement at 12 months post-op. This advance knowledge may aid LRYGB planning and improve outcomes.

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http://dx.doi.org/10.1016/j.amjsurg.2018.11.003DOI Listing

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