A novel controlled release system based on Tragacanth nanofibers loaded Peppermint oil.

Carbohydr Polym

Textile Engineering Department, Functional Fibrous Structures & Environmental Enhancement (FFSEE), Amirkabir University of Technology, Tehran, Iran. Electronic address:

Published: February 2019

In this paper, a novel controlled release system based on Tragacanth nanofibers loaded with Peppermint oil is introduced by using a sonochemical/microemulsion method. The synthesized Tragacanth nanofibers showed a one-dimensional shape with 58 nm thickness and relatively smooth surface. Also, the loading of Peppermint oil into the synthesized nanofibers confirmed with FT-IR spectra. Further, a relatively good controlled release property (92.38%) reported for the loaded Peppermint oil nanofibers after 18 h. Finally, the synthesized nanofibers loaded with 18.3% Peppermint oil presented reasonably good antibacterial activities against E. coli and S. aureus and a low-cytotoxicity against human fibroblast cells as the most important properties.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.carbpol.2018.10.078DOI Listing

Publication Analysis

Top Keywords

peppermint oil
20
controlled release
12
tragacanth nanofibers
12
nanofibers loaded
12
loaded peppermint
12
novel controlled
8
release system
8
system based
8
based tragacanth
8
synthesized nanofibers
8

Similar Publications

Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of an essential oil from the aerial parts of  ×  L. (peppermint oil) when used as a sensory additive in feed and in water for drinking for all animal species. The EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) concluded that that peppermint oil is safe for all animal species at the maximum use level of 12 mg/kg complete feed.

View Article and Find Full Text PDF
Article Synopsis
  • Tyrosine kinase inhibitors like tofacitinib (TCB) are effective in treating psoriasis, and this study aims to enhance TCB's effectiveness while minimizing side effects through a new topical emulgel formulation.
  • The emulgel was created by combining TCB with various ingredients, resulting in a formulation with ideal viscosity, firmness, and controlled release of the drug over 24 hours.
  • The new TCB-emulgel showed significantly improved anti-psoriatic effects in a mouse model, reducing psoriasis severity scores and inflammation markers compared to existing treatments, supporting its potential for clinical use in managing psoriasis.
View Article and Find Full Text PDF

Adjunct Therapies to Standard Care for IBS and IBD Patients: Digestive Symptoms Improvement and Quality of Life Optimization.

Nutrients

November 2024

RNI-Product-Life Group, RNI Conseil, 17 Rue des 2 Haies, 49100 Angers, France.

The prevalence of both inflammatory bowel diseases (IBD) and Irritable Bowel Syndrome (IBS) is increasing, with persistent digestive symptoms, an altered quality of life, and higher rates of anxiety, chronic fatigue, and sleep trouble than the general population. This scoping review will analyze the latest clinical practice recommendations and clinical studies on non-pharmaceutical interventions such as diet adaptations, physical activity, cognitive behavioral therapies, and medical nutrition therapies such as probiotics, soluble fibers, chitin-glucan, and micronutrients for digestive symptoms relief, quality of life improvement and nutritional deficiencies correction in IBS and IBD patients. The objective is to help healthcare practitioners and dietitians to build personalized care program for IBD and IBS patients.

View Article and Find Full Text PDF

Gastric cancer (GC) represents one of the most lethal forms of cancer. When identified at an early stage, conventional treatment can be curative. The key to identifying GC at an early stage is high-quality esophagogastroduodenoscopy (EGD).

View Article and Find Full Text PDF

Androgenetic alopecia is a chronic dermatological condition in which genetically predisposed individuals undergo progressive hair loss secondary to the effects of circulating androgens. It has been well documented that dihydrotestosterone binds to the androgenic receptors prevalent in the scalp, thus inducing miniaturization of the hair follicle. To date, the only FDA approved medications for the treatment of androgenetic alopecia are finasteride and minoxidil.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!