Antifungal, anti-inflamatory and neuritogenic activity of newly-isolated compounds from .

Nat Prod Res

College of Chemistry & Pharmacy, Shaanxi Key Laboratory of Natural Products & Chemical Biology, Northwest A&F University, Yangling, P. R. China.

Published: June 2020

A new ester () and a terpenoid () were isolated from the dried whole plant of (H) E. ex D for the first time and their structures were elucidated, as well as their biological activities are described. The two compounds all showed good antifungal activities, especially furanone () exhibited better antifungal activity against and with EC value of 22.82, 18.90 g/mL, respectively. Compound exhibited a significant promotion on the neurite outgrowth in NGF-induced PC-12 cells, and moderate inhibition on the NO production induced by lipopolysaccharide (LPS) in BV-2 microglial cells.

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http://dx.doi.org/10.1080/14786419.2018.1519709DOI Listing

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