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http://dx.doi.org/10.1016/j.cell.2018.11.003 | DOI Listing |
Phys Med Biol
January 2025
Beijing institute of control and electronic technology, 51 Beilijia, Muxidi, Xicheng District, Beijing 100038, Beijing, 100038, CHINA.
Objective Ultrasound is the predominant modality in medical practice for evaluating thyroid nodules. Currently, diagnosis is typically based on textural information. This study aims to develop an automated texture classification approach to aid physicians in interpreting ultrasound images of thyroid nodules.
View Article and Find Full Text PDFSci Rep
January 2025
Neuro-Robotics Lab, Department of Robotics, Graduate School of Engineering, Tohoku University, Sendai, Japan.
Humans exploit motor synergies for motor control; however, how they emerge during motor learning is not clearly understood. Few studies have dealt with the computational mechanism for generating synergies. Previously, optimal control generated synergistic motion for the upper limb; however, it has not yet been applied to the high-dimensional whole-body system.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
University of Exeter, Exeter, United Kingdom.
Background: The J20 mouse is an established model of amyloid pathology, exhibiting neuropathological and behavioural symptoms reflective of human Alzheimer's disease (AD). Previous work, conducted by Castanho et al (2020), revealed transcriptomic change in the hippocampus of J20 mice to be associated with the accumulation of amyloid pathology. Here, we investigated the spatial distribution of such transcriptomic changes using novel spatial transcriptomic technology.
View Article and Find Full Text PDFCancer Biol Med
January 2025
Department of Diagnostic and Therapeutic Ultrasonography, Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin's Clinical Research Center for Cancer, Tianjin 300060, China.
Artificial intelligence (AI) is significantly advancing precision medicine, particularly in the fields of immunogenomics, radiomics, and pathomics. In immunogenomics, AI can process vast amounts of genomic and multi-omic data to identify biomarkers associated with immunotherapy responses and disease prognosis, thus providing strong support for personalized treatments. In radiomics, AI can analyze high-dimensional features from computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography/computed tomography (PET/CT) images to discover imaging biomarkers associated with tumor heterogeneity, treatment response, and disease progression, thereby enabling non-invasive, real-time assessments for personalized therapy.
View Article and Find Full Text PDFNat Commun
January 2025
State Key Laboratory of Information Photonics and Optical Communications, Beijing University of Posts and Telecommunications, Beijing, China.
Complex-valued neural networks process both amplitude and phase information, in contrast to conventional artificial neural networks, achieving additive capabilities in recognizing phase-sensitive data inherent in wave-related phenomena. The ever-increasing data capacity and network scale place substantial demands on underlying computing hardware. In parallel with the successes and extensive efforts made in electronics, optical neuromorphic hardware is promising to achieve ultra-high computing performances due to its inherent analog architecture and wide bandwidth.
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