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Oesophageal motility disorders: rapid functional diagnosis using computerised radionuclide oesophageal transit study.
Singapore Med J
June 1995
Division of Nuclear Medicine, University Hospital, Kuala Lumpur, Malaysia.
Ten patients presenting with central chest pain and/or dysphagia were diagnosed to have oesophageal motility disorders (OMD) with an incoordinate motor function using computerised radionuclide oesophageal transit study (RT). The criteria for diagnosis of OMD with incoordination using RT were: an 'incoordinate' or 'to and fro' pattern characterised by multiple peaks of activity, prolonged total transit time or radionuclide bolus through entire length of oesophagus and a significant portion of bolus entering the stomach. These features are characteristic but not pathognomonic of diffuse oesophageal spasm (DES) as they are also seen in non-specific motility disorders (NSMD) and occasionally in order oesophageal motility disorders.
View Article and Find Full Text PDFRelation of hypocapnic symptoms to rate of fall of end-tidal PCO2 in normal subjects.
Respir Med
July 1992
Department of Physiology, Kings College, London, U.K.
Hyperventilation is of little clinical relevance unless it causes symptoms. These are often non-specific. Their threshold for onset and relation to steady level of arterial (or its equivalent, end-tidal PCO2; PETCO2) are uncertain, and it has been suggested that they may relate better to the rate of fall of PCO2 than to the absolute level.
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