This article provides guidelines on the definition, nomenclature, and classification of cirrhosis, hepatic fibrosis, and chronic hepatitis. Cirrhosis is considered according to its etiology and morphological characteristics, these being complementary rather than alternative.
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Current insights and challenges in the management of perifoveal vascular anomalous complex (PVAC): a systematic review of multimodal imaging features and treatment strategies.
Eye (Lond)
December 2024
IRCCS Ospedale Policlinico San Martino, Eye Unit, Genova, Italy.
The aim of this article is to comprehensively review the multimodal imaging (MMI) features that define perifoveal vascular anomalous complex (PVAC) and to update the optimal treatment strategies for this disorder with a focus also on the underlying pathogenetic mechanisms. This systematic review was performed based on a search of the PubMed and Embase databases of relevant papers on the subject of PVAC. PVAC is characterized by well-defined MMI findings, including remarkable morphological features with optical coherence tomography (OCT) and OCT angiography (OCTA).
View Article and Find Full Text PDFRecent years have seen the development of various classifications of muscle injuries, primarily based on the topographic location within the bone-tendon-muscle chain. This paper proposes an enhanced nomenclature for muscle injuries that incorporates histoarchitectural definitions alongside topographic classifications, emphasizing the importance of connective tissue damage characterization. A detailed understanding of the distinct anatomical and histological characteristics of tendon, aponeurosis, and fascia is essential for consistent terminology.
View Article and Find Full Text PDFValidation and epidemiologic definition of the novel steatotic liver disease nomenclature in a national United States cohort with cirrhosis.
Clin Gastroenterol Hepatol
December 2024
Division of Gastroenterology and Hepatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Department of Medicine, Corporal Michael J. Crescenz VA Medical Center, Philadelphia, Pennsylvania, USA. Electronic address:
Background And Aims: Novel steatotic liver disease (SLD) definitions were introduced in 2023. Accurate and meaningful classifications using clinical data are needed to study interventions and outcomes.
Methods: In a national cohort of Veterans with cirrhosis and imaging-confirmed steatosis, seven algorithms differentially emphasizing cardiometabolic risk factors (CMRFs) and alcohol exposure were developed to define alcohol-associated liver disease (ALD), metabolic dysfunction associated SLD (MASLD), and MASLD with increased alcohol intake (MetALD).
How I diagnose high-grade B-cell lymphoma.
Am J Clin Pathol
December 2024
Mayo Clinic Arizona, Phoenix, AZ, US.
Objectives: High-grade B-cell lymphoma (HGBL), introduced in the 2016 World Health Organization (WHO) revised fourth edition classification, included cases defined by MYC and BCL2 and/or BCL6 rearrangements or by high-grade morphology. Diagnostic criteria and nomenclature for these lymphomas were refined in the 2022 WHO fifth edition (WHO-5) classification and International Consensus Classification (ICC). This review describes our approach to the diagnosis of HGBL.
View Article and Find Full Text PDFPneumothorax resulting from injury is a common phenomenon in both civilian and military trauma. A pneumothorax or simple pneumothorax is defined as air in the pleural space. A tension pneumothorax can evolve from a simple pneumothorax if there is a continued air leak from the lung without mechanism for egress.
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