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Cerebral Infectious Opportunistic Lesions in a Patient with Acute Myeloid Leukaemia: The Challenge of Diagnosis and Clinical Management.
Antibiotics (Basel)
April 2024
Department of Health Sciences, University of Milan Bicocca, 20126 Milan, Italy.
Central nervous system (CNS) lesions, especially invasive fungal diseases (IFDs), in immunocompromised patients pose a great challenge in diagnosis and treatment. We report the case of a 48-year-old man with acute myeloid leukaemia and probable pulmonary aspergillosis, who developed hyposthenia of the left upper limb, after achieving leukaemia remission and while on voriconazole. Magnetic resonance imaging (MRI) showed oedematous CNS lesions with a haemorrhagic component in the right hemisphere with lepto-meningitis.
View Article and Find Full Text PDFUsual Presentation Of An Unusual Pathogen - Cryptococcus Laurentii Meningitis: A Case Report.
J Pak Med Assoc
October 2023
Department of Pathology, Army Medical College, National University of Medical Sciences, Rawalpindi, Pakistan.
Infections caused by non-neoformans Cryptococcus spp., including Cryptococcus laurentii, previously thought to be saprophyte and non-pathogenic, have become more common during the past few years, particularly in immunocompromised hosts. To the best of our knowledge here, we present the first case of meningitis in an immunocompromised patient due to a fungus that has never been reported in Pakistan.
View Article and Find Full Text PDF[Contribution to the knowledge of the "periostitis ossificans interna" of the cranial vault (author's transl)].
Zentralbl Allg Pathol
September 1979
An unusual observation of hyperostosis of the frontal bone exhibiting five alternating layers of compact and cancellous bone on cross section is demonstrated. The peculiar, hitherto not described hyperostosis occurred in an 18 year old female suffering from recurrent chronical pachy- and lepto-meningitis since birth. A second similar observation was made in a 15 year old male, trepanated because of an epidural abscess.
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