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Evaluating osteopontin as a biomarker of obesity related complications before and after metabolic and bariatric surgery: A systematic review and meta-analysis.
Obes Res Clin Pract
January 2025
Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno D'Alcontres, 31, Messina 98166, Italy. Electronic address:
Background/objectives: Obesity is a major public health concern, significantly elevating the risk of developing comorbid conditions such as type 2 diabetes mellitus and cardio-vascular diseases, while also shortening life expectancy. Currently, metabolic and bariatric surgery (MBS) is one of the most effective long-term interventions for achieving substantial weight loss, alongside notable improvements in overall quality of life. However, evidence suggests that these procedures may negatively affect bone health, leading to an increased risk of fractures.
View Article and Find Full Text PDFCorrection: Surgical stabilization of rib fractures (SSRF): the WSES and CWIS position paper.
World J Emerg Surg
January 2025
Department of General and Emergency Surgery, Anesthesia and Intensive Care Unit, Maurizio Bufalini Hospital, Cesena, Italy.
Generation of a human induced pluripotent stem cell line (BIHi292-A) from PBMCs of a female patient diagnosed with Nasu-Hakola disease (NHD)/polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL) carrying a novel heterozygous mutation in the TREM2 gene.
Stem Cell Res
January 2025
Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Klinik für Neurologie und Abteilung für Experimentelle Neurologie, Charitéplatz 1, 10117 Berlin, Germany.
NHD/PLOSL is an orphan disease characterized by progressive presenile dementia associated with recurrent fractures due to polycystic bone lesions. In this study, we generated the human induced pluripotent stem cell (hiPSC) line BIHi292-A from a 30-year-old women diagnosed with NHD/PLOSL, carrying two compound heterozygous frameshift mutations [c.313del (p.
View Article and Find Full Text PDFA new in situ fracturing-enhanced oxidative remediation for various low-permeability phenanthrene-contaminated soils: Oxidation effectiveness and kinetics of potassium permanganate.
J Hazard Mater
January 2025
Department of Geotechnical Engineering, Tongji University, Shanghai 200092, China; Key Laboratory of Geotechnical and Underground Engineering of the Ministry of Education, Shanghai 200092, China.
A new in situ fracturing-enhanced oxidative remediation approach was recommended in this study to achieve rapid and efficient remediation of low-permeability contaminated sites. The objective of this study was to evaluate the effects of permeability and potassium permanganate (KMnO) concentration on the oxidation effectiveness and kinetics of KMnO in phenanthrene (PHE)-contaminated soil through rigid-wall hydraulic conductivity tests and a series of laboratory experiments. The results indicate that for various low-permeability contaminated soils, there was a critical KMnO concentration to significantly reduce the remediation time and a critical Darcy velocity to meet remediation goals.
View Article and Find Full Text PDFSurgical management and outcomes of pure sacroiliac joint dislocations: A systematic review.
J Orthop
August 2025
University of Turin, Centro Traumatologico Ortopedico (CTO), Department of Orthopaedic Surgery, Turin, Italy.
Introduction: Sacroiliac joint (SIJ) dislocations, particularly pure SIJ dislocations without associated fractures, represent a rare and complex subset of pelvic ring injuries. Given the intricate pelvic anatomy and the need to achieve both stability and functional recovery, the optimal surgical management for these injuries remains a topic of debate. This systematic review aims to evaluate the various surgical techniques employed in treating this rare and challenging injury and assess associated clinical outcomes and complications.
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