AI Article Synopsis
- This study explores a new method for locating non-palpable breast tumors using a small steel marker and SPIO nanoparticles for sentinel node detection, employing a magnetic probe.
- Ten patients with confirmed breast carcinoma participated, and all tumors were safely removed with adequate surgical margins.
- The technique demonstrated a mean detection rate of 3.4 sentinel nodes per patient without interference from markers, enhancing the efficiency of breast surgery.
Article Abstract
Aim: In this study we used a new technology for localization of non-palpable breast tumors using a small steel marker in conjunction of sentinel nodes (SLNs) detection through injection of SPIO nanoparticles; both detected through a magnetic probe. Materials & methods: Ten patients with biopsy-proven nonpalpable invasive breast carcinoma or premalignant lesions eligible for SLNs biopsy were enrolled in this study.
Results: All tumors were removed with safe surgical margins. The mean nodal detection rate was 3.4 nodes per patient. No interferences in magnetic probe measurements due to the presence of both markers in the same breast were observed.
Conclusion: Simultaneous use of the magnetic method in localization of impalpable breast tumors and SNs detection makes breast surgery convenient.
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| http://dx.doi.org/10.2217/nnm-2018-0220 | DOI Listing |
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