Experiments have suggested that the conical nanopore may be a reasonable sensor for the biopolymer analysis as it can provide high-resolution current signal. In this paper, we use Langevin dynamics simulation to study the translocation of charged polymer (polyelectrolyte) through three different conical nanopores, a single-conical nanopore with large entry and small exit (pore I), a single-conical nanopore with small entry and large exit (pore II), and a double-conical nanopore with the tip (narrowest place) at the middle (pore III). Simulation shows that the detailed translocation behaviors are of pore structure dependence. Pore I might be the most reasonable one for the polyelectrolyte analysis, especially at strong monomer-pore attraction, since it can efficiently reduce the polyelectrolyte speed at the tip. The simulation results are interpreted by the free energy profiles of the polyelectrolyte translocation through different pores and the time of individual monomer passing through the tips.
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