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Effect of Hyaluronic Acid Added to Suture Material and its Relationship with Bacterial Colonization: An Study. | LitMetric
Aims And Objectives : The aims of this study were to evaluate the presence of and , in polyglycolic acid (PGA) 4-0 and silk sutures, with or without hyaluronic acid (HA) treatment.Materials And Methods : This study measured and growth on PGA and silk sutures, through incubation in agar media for 24 h. The suture length was 10 cm and divided into three parts: A (8 h), B (16 h), and C (24 h), which were observed every 8 h, followed by suspension on a microscopic slide. This was repeated thrice. The number of and cells was recorded and compared between the suture types.Results : The mean colony forming units (CFUs) differed at each time point between non-HA and HA-PGA sutures ( = 0.0016), with a greater number of CFUs on non-HA-PGA. The mean CFUs were significantly higher on non-HA silk than on HA-silk sutures ( = 0.008). There was a significant increase in CFUs on non-HA silk than on HA-silk sutures ( = 0.008). CFUs were higher on non-HA-PGA than on HA-PGA sutures ( = 0.006). We performed repeated measures two-way ANOVA (SPSS version 13.0) for comparison between group factors and time points and analysis using independent samples -test.Conclusions : HA reduced wicking in both PGA and silk sutures.
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