Osteogenesis Imperfecta and Extra-/Intradural Hematomas: A Case Report and Review of the Literature.

J Pediatr Genet

Department of Neurosurgery, Ankara University School of Medicine, Ibni Sina Hospital, Ankara, Turkey.

Published: December 2018

Osteogenesis imperfecta, also named as brittle bone disease, is characterized by fragile bones and short stature caused by mutations in the collagen gene. Subdural and intraparenchymal hematomas are defined and associated with trauma, vascular causes, and systemic bleeding diathesis. Skull fragility may lead to epidural hematoma, which is a life-threatening situation. Vascular fragility and intrinsic platelet defects are the causes of bleeding in patients with osteogenesis imperfecta, which is a major management challenge for neurosurgeons. Here, we reported on a 5-year-old boy with osteogenesis imperfecta with epidural hematoma and skull fracture following a trivial trauma, and made a literature review of 28 cases with extra-/intradural hematoma.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234040PMC
http://dx.doi.org/10.1055/s-0038-1660826DOI Listing

Publication Analysis

Top Keywords

osteogenesis imperfecta
16
epidural hematoma
8
osteogenesis
4
imperfecta extra-/intradural
4
extra-/intradural hematomas
4
hematomas case
4
case report
4
report review
4
review literature
4
literature osteogenesis
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!