Introduction: Asthma is a multiphenotypic disease, and therapeutic managenment in patients with severe asthma is particulary difficult, with conventional treatment of severe asthma showing poor efficacy.
Aim: To analyse forced expiratory volume in 1 s (FEV) following the adminstration of omalizumab.
Material And Methods: Six patinents (mean age: 50 ±12.6) with severe, uncontrolled asthma according to the GINA guidelines were enrolled in the study.
Results: Treatment with omalizumab increased in all subjects FEV by 17.28 ±13.4% after months and 18.57 ±13.4% after 12 months of treatment.
Conclusions: These results provides further evidence that therapy with omalizumab improves spiromtric parameters in severe asthma.
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| http://dx.doi.org/10.5114/ada.2018.77241 | DOI Listing |
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