We report the long term results of interstitial irradiation therapy in patients suffering from malignant supratentorial gliomas. The radioisotopes implanted by stereotaxic technique were Au198 grains in solid tumors and Y90 colloidal solution in a cystic tumor. The therapy was always well tolerated. Minimum survival time after implantation was 9 months, maximum exceeded 52 months. In all cases interstitial irradiation therapy solved or drastically diminished the severe secondary epilepsy from which all the patients suffered.
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