AI Article Synopsis
- The study investigated whether early surgical birth defects in individuals with Down syndrome contribute to differences in cognitive and behavioral outcomes.
- Despite analyzing data from the Down Syndrome Cognition Project involving 234 participants aged 6-25, the researchers found no link between these birth defects and lower functioning.
- The findings suggest that these medical issues do not significantly impact cognitive or behavioral outcomes when accounting for other factors like gender, race/ethnicity, and socioeconomic status.
Article Abstract
The cause of the high degree of variability in cognition and behavior among individuals with Down syndrome (DS) is unknown. We hypothesized that birth defects requiring surgery in the first years of life (congenital heart defects and gastrointestinal defects) might affect an individual's level of function. We used data from the first 234 individuals, age 6-25 years, enrolled in the Down Syndrome Cognition Project (DSCP) to test this hypothesis. Data were drawn from medical records, parent interviews, and a cognitive and behavior assessment battery. Results did not support our hypothesis. That is, we found no evidence that either birth defect was associated with poorer outcomes, adjusting for gender, race/ethnicity, and socioeconomic status. Implications for study design and measurement are discussed.
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Source |
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7100339 | PMC |
| http://dx.doi.org/10.1352/1944-7558-123.6.514 | DOI Listing |
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