We reviewed all outpatients with bone and joint infection treated with cefoxitin in continuous intravenous infusion using mobile elastomeric infusors in our regional reference center between 2014 and 2017. The stability of cefoxitin provides an interesting and well-tolerated alternative for continuous infusion in outpatients with polymicrobial bone and joint infection.
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http://dx.doi.org/10.7150/jbji.27718 | DOI Listing |
Sci Rep
December 2024
Department of Orthopedic Surgery, Arthroscopy and Joint Research Institute, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
The humeral head is the second most common anatomical site of osteonecrosis after the femoral head. Studies have reported satisfactory clinical outcomes after shoulder arthroplasty to treat osteonecrosis of the humeral head (ONHH). However, there are concerns regarding implant longevity in relatively young patients.
View Article and Find Full Text PDFOral Dis
December 2024
Department of Oral and Maxillofacial Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.
Objectives: The effects of systemic inflammation on the temporomandibular joint (TMJ) are poorly understood. This study aimed to establish a mouse model to study the effects of systemic inflammation on the TMJ.
Materials And Methods: SKG mice, a BALB/c strain with spontaneous onset of rheumatoid arthritis-like symptoms due to a spontaneous point mutation (W163C) in the gene encoding the SH2 domain of ZAP-70, were treated with zymosan (β-1,3-glucan).
J Exp Orthop
January 2025
Department of Orthopedic Surgery and Traumatology, Freiburg University Hospital Albert Ludwigs University Freiburg Freiburg Germany.
Introduction: The medial patellofemoral ligament (MPFL) is the main patellar stabilizer in low knee flexion degrees (0-30°). Isolated MPFL reconstruction (MPFLr) is therefore considered the gold standard of surgical procedures for low flexion patellofemoral instabilities (PFIs). Despite excellent clinical results, little is known about the effect of MPFLr on kinematic parameters (KPs) of the patellofemoral joint in vivo.
View Article and Find Full Text PDFCureus
November 2024
Department of Orthopaedic Surgery, Iwaki City Medical Center, Iwaki, JPN.
Suprascapular nerve entrapment caused by intraosseous cystic lesions is a rare condition. We present the case of a 49-year-old man with right shoulder numbness, slight infraspinatus (ISP) weakness, and shoulder pain. He underwent open surgery and arthroscopic evaluation.
View Article and Find Full Text PDFCureus
November 2024
Division of Musculoskeletal Oncology and Orthopaedics Surgery, Tochigi Cancer Center, Utsunomiya, JPN.
Soft tissue and bone tumors are rare, and their low frequency and diverse histological types make conducting large-scale clinical trials challenging. Patient-derived xenografts (PDX), entailing implantation of cancer specimens in immunocompromised mice, are emerging as a valuable translational model because PDX keeps the original tumors' character and drug sensitivity. We sequentially transplanted 166 surgical and biopsy specimens from orthopedic surgeries, including 138 soft tissue and bone tumors (81 malignant, 23 intermediate, and 34 benign), 16 metastatic bone tumors, 9 hematological malignancies, and 3 non-tumor tissues.
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