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Genetic Variants and Lifestyle Factors in Androgenetic Alopecia Patients: A Case-Control Study of Single Nucleotide Polymorphisms and Their Contribution to Baldness Risk.
Nutrients
January 2025
Epidemiology Unit, Istituto Dermopatico dell'Immacolata (IDI-IRCCS-FLMM), 00167 Rome, Italy.
Unlabelled: Single nucleotide polymorphisms (SNPs) found to be associated with Androgenetic Alopecia (AGA) to date, are characterized by an apparent reduced penetrance into the phenotype suggesting a role of other factors in the etiology of AGA.
Objective: We conducted a study to investigate the role of specific allelic variants in AGA controlling for nutritional and lifestyle factors.
Methods: Individual patterns of SNPs present in the baldness susceptibility locus at 20p11 (rs1160312 and rs6113491) or close to the androgen receptor (AR) gene in chromosome X (rs1041668) were investigated in 212 male subjects.
An Asset-Based Examination of Contextual Factors Influencing Nutrition Security: The Case of Rural Northern New England.
Nutrients
January 2025
Food Systems Program, University of Vermont, Burlington, VT 05405, USA.
Background/objectives: Rural communities face a disproportionate burden in terms of diet-related health challenges and have been identified as a target for the U.S. Department of Agriculture's nutrition security initiatives.
View Article and Find Full Text PDFTwo- and Three-Dimensional Culture Systems: Respiratory In Vitro Tissue Models for Chemical Screening and Risk-Based Decision Making.
Pharmaceuticals (Basel)
January 2025
MatTek Corporation, Ashland, MA 01721, USA.
Risk of lung damage from inhaled chemicals or substances has long been assessed using animal models. However, New Approach Methodologies (NAMs) that replace, reduce, and/or refine the use of animals in safety testing such as 2D and 3D cultures are increasingly being used to understand human-relevant toxicity responses and for the assessment of hazard identification. Here we review 2D and 3D lung models in terms of their application for inhalation toxicity assessment.
View Article and Find Full Text PDFCarbon Nanosphere-Based TiO Double Inverse Opals.
Molecules
January 2025
Institute of Physical Metallurgy, Metal Forming and Nanotechnology, University of Miskolc, H-3515 Miskolc, Hungary.
Inverse opals (IOs) are intensively researched in the field of photocatalysis, since their optical properties can be fine-tuned by the initial nanosphere size and material. Another possible route for photonic crystal programming is to stack IOs with different pore sizes. Accordingly, single and double IOs were synthesized using vertical deposition and atomic layer deposition.
View Article and Find Full Text PDFKey Insights into Respiratory Virus Testing: Sensitivity and Clinical Implications.
Microorganisms
January 2025
Zentrum für Notfallmedizin, Universitätsmedizin Essen, 45147 Essen, Germany.
Acute respiratory infections are a significant challenge in primary care and hospital settings. Viruses are the most common etiology and the overlapping symptomatology among major respiratory viruses, such as influenza, severe acute respiratory syndrome coronavirus 2, and respiratory syncytial virus, requires the use of diagnostic tests that deliver early and accurate results. With the increasing availability of rapid antigen tests (RATS), it is tempting to prefer them over polymerase chain reaction (PCR) tests.
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