Introduction: There is a paucity of survival data reporting the medium to long-term outcome of the LINK® Endo-Model rotational hinge total knee arthroplasty (ERH-TKA). Such information is essential when counselling patients and predictors of survival would help inform patients of their likely outcome.
Materials And Methods: A series of patients, who received an ERH-TKA, with a minimum follow-up of 5 years, were retrospectively identified from an established arthroplasty database. Data were collected from paper and electronic patient records. This included patient demographics, indication for surgery, complication rates and revision status. Our primary outcome of interest was joint implant survival.
Results: One hundred patients underwent an ERH-TKA over an 11-year period. There were 66 females and 34 males, with a mean age of 73.8 years and 67.6 years, respectively. Indications were classified into primary (n = 41), aseptic revision (n = 47) and two-stage infective revision (n = 12). The median follow-up was 8.2 (range 5-12) years. One-year implant survival amongst the cohort was 99%, falling to 95% at 5 years. Overall, there were eight revisions during the follow-up period. Considering only cases of aseptic failure, survival was 97% at 5 years and all failures occurred amongst revision cases. Implant failure was greater following revision arthroplasty but this was not statistically significant (p = 0.97). Cox regression analysis identified male sex to be the only independent predictor of failure (hazard ratio 1.75, 95% CI 1.04-31.82, p = 0.04) after adjusting for confounding variables.
Conclusions: The ERH-TKA has a good medium- to long-term survival rate but male patients are nearly twice as likely to undergo revision, compared to females, and should be made aware of this preoperatively.
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http://dx.doi.org/10.1007/s00402-018-3064-0 | DOI Listing |
Environ Sci Technol
January 2025
Saudi Aramco, Dhahran 31311, Saudi Arabia.
Amid ambitious net-zero goals and growing demands for freight logistics, addressing the climate challenges posed by the heavy-duty truck (HDT) sector is an urgent and pivotal task. This study develops an integrated HDT model by incorporating vehicle dynamic simulation and life cycle analysis to quantify energy consumption, greenhouse gas (GHG) emissions, and total cost of ownership associated with three emerging powertrain technologies in various truck use scenarios in China, including battery electric, fuel cell electric, and hydrogen combustion engine trucks. The results reveal varying levels of economic suitability for these powertrain alternatives depending on required driving ranges and duty cycles: the battery electric for regional-haul applications, the hydrogen fuel cell for longer-haul and low-load driving conditions, and the hydrogen combustion engine to meet high power requirements.
View Article and Find Full Text PDFCureus
December 2024
Orthopedic Surgery, Sengkang General Hospital, Singapore, SGP.
Background: Femoral condyle insufficiency fractures following total knee arthroplasty (FCIF-TKA) are rare but significant complications. These fractures, characterized by atraumatic bone insufficiency near the femoral component, present unique challenges in postoperative care, often necessitating femoral component revision.
Methods: This study retrospectively reviewed 835 primary total knee arthroplasties performed by a single surgeon, identifying six cases of FCIF-TKA.
J Virol
January 2025
Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles (UCLA), Los Angeles, California, USA.
Discovered in 1994 in lesions of an AIDS patient, Kaposi's sarcoma-associated herpesvirus (KSHV) is a member of the gammaherpesvirus subfamily of the family, which contains a total of nine that infect humans. These viruses all contain a large envelope glycoprotein, glycoprotein B (gB), that is required for viral fusion with host cell membrane to initial infection. Although the atomic structures of five other human herpesviruses in their postfusion conformation and one in its prefusion conformation are known, the atomic structure of KSHV gB has not been reported.
View Article and Find Full Text PDFSci Total Environ
January 2025
Wildlife Health Lab, Animal Health Diagnostic Center, College of Veterinary Medicine, Cornell University, 240 Farrier Rd, Ithaca, NY 14853, USA. Electronic address:
Waterfowl serve as indicators of ecosystem health and represent a pathway of contaminant exposure for hunters who consume them. In the northeast Atlantic Flyway, data on baseline contaminant loads in waterfowl are lacking. We assessed five species of commonly harvested (and consumed) waterfowl for mercury, polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans, polychlorinated biphenyls (PCBs), organochlorine pesticides (OCPs), and per- and polyfluoroalkyl substances (PFAS).
View Article and Find Full Text PDFBMC Womens Health
January 2025
Hinge Health, Inc, 455 Market Street, Suite 700, San Francisco, CA, 94105, USA.
Background: Chronic pelvic pain is a common yet undertreated condition that significantly impacts quality of life for women worldwide. Digital exercise therapy designed to target pelvic pain can improve symptomology while reducing time and cost-related barriers to in-person clinical care.
Methods: This longitudinal, observational study of a digital women's pelvic health program examined pelvic pain, anxiety, and depression at 4 and 12 weeks in female adults experiencing chronic pelvic pain.
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