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BMC Infect Dis
January 2025
Department of Development and Regeneration, KU Leuven, Louvain, Belgium.
Background: Non-typhoidal Salmonella (NTS) frequently cause bloodstream infection in children under-five in sub-Saharan Africa, particularly in malaria-endemic areas. Due to increasing drug resistance, NTS are often not covered by standard-of-care empirical antibiotics for severe febrile illness. We developed a clinical prediction model to orient the choice of empirical antibiotics (standard-of-care versus alternative antibiotics) for children admitted to hospital in settings with high proportions of drug-resistant NTS.
View Article and Find Full Text PDFPathogens
January 2025
Research Group of Microbiology, Industry and Environment (GIMIA), Faculty of Basic Sciences, Universidad Santiago de Cali, Cali 760035, Colombia.
Non-typhoidal salmonellosis is a foodborne disease caused by spp. Most outbreaks of this disease are commonly associated with consuming contaminated meat products, hence the importance of monitoring ready-to-eat artisanal pork sausages for the presence of these bacteria. A total of 494 samples of grilled and smoked barbecue artisanal pork sausages were collected at food outlets from 12 municipalities of the Department of Quindío, Colombia, between 2017 and 2022.
View Article and Find Full Text PDFVaccines (Basel)
December 2024
Food Hygiene and Nutrition Service, Local Health Unit 3, Department of Prevention, 16142 Genoa, Italy.
is considered the major zoonotic and foodborne pathogen responsible for human infections. It includes the serovars causing typhoid fever ( and ) and the non-typhoidal salmonella (NTS) serovars ( and ), causing enteric infections known as "Salmonellosis". NTS represents a major public health burden worldwide.
View Article and Find Full Text PDFCureus
December 2024
General Medicine, Sikkim Manipal Institute of Medical Sciences and Central Referral Hospital, Gangtok, IND.
William Budd (1811-1880) was a pioneering British physician whose work on infectious diseases, particularly typhoid fever, significantly advanced the understanding of epidemiology and public health in the 19th century. This review examines Budd's life, medical career, and groundbreaking contributions to the study of infectious diseases, focusing on his influential research into the transmission of typhoid fever, advocacy for public health reforms, and lasting legacy in epidemiology. Through meticulous research and innovative thinking, Budd laid the groundwork for modern approaches to disease control and prevention, cementing his place as a key figure in medical history.
View Article and Find Full Text PDFGates Open Res
January 2025
Liverpool School of Tropical Medicine, Liverpool, England, UK.
Typhoid fever is a significant public health problem endemic in Southeast Asia and Sub-Saharan Africa. Antimicrobial treatment of typhoid is however threatened by the increasing prevalence of antimicrobial resistant (AMR) Typhi, especially in the globally successful lineage (4.3.
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