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Living Donor Liver Transplant as Rescue Surgery for a Patient with Hepatocellular Carcinoma Who Underwent Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS). | LitMetric

AI Article Synopsis

  • The ALPPS technique is used to promote liver growth in patients with liver tumors, but can lead to complications if liver function deteriorates.
  • A 49-year-old man with liver cancer switched from a standard liver resection to ALPPS, but experienced liver failure post-surgery.
  • A living donor liver transplant successfully rescued the patient, resulting in a smooth recovery without complications after three months.

Article Abstract

BACKGROUND The associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) is an important tool to induce fast liver hypertrophy. The degree of hepatic fibrosis/cirrhosis in patients with HCC negatively impacts their health, and the risk of liver failure is always present. In these cases, liver transplantation may be necessary as a rescue procedure. We present the case of a patient with HCC who underwent ALPPS and developed liver failure. A living donor liver transplant was performed as a rescue procedure. CASE REPORT A 49-year-old man with chronic hepatitis B without cirrhosis underwent computed tomography, which revealed an expansive lesion in the right lobe of his liver that was diagnosed as hepatocellular carcinoma. Liver resection was indicated and liver cirrhosis was observed with high portal pressure after transection. The treatment strategy was switched from right hepatectomy to ALPPS. The patient developed severe liver dysfunction and liver transplantation was indicated. His postoperative course was uneventful and 3 months after the procedure the patient was without complications. CONCLUSIONS Living donor liver transplantation may be necessary as a rescue procedure for patients who underwent ALPPS and develop liver dysfunction.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238545PMC
http://dx.doi.org/10.12659/AJCR.911694DOI Listing

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