Laparoscopic Gastric Plication versus Laparoscopic Sleeve Gastrectomy: An Up-to-Date Systematic Review and Meta-Analysis.

Introduction: A meta-analysis was conducted in order to provide an up-to-date comparison of laparoscopic sleeve gastrectomy (LSG) and laparoscopic gastric plication (LGP) for morbid obesity.

Materials And Methods: The PRISMA guidelines and were used for the conduction of this study. A systematic literature search was performed in the electronic databases (MEDLINE, CENTRAL, and Web of Science and Scopus). The fixed effects or random effects model was used according to the Cochran Q test.

Results: Totally, 12 eligible studies were extracted. LSG displayed a statistically significant lower rate of overall complications (OR: 0.35; 95% CI: 0.17, 0.68; =0.002) and a sustainable higher %EWL through all time endpoints (OR: 4.86, =0.04; OR: 7.57, < 0.00001; and OR: 13.74; < 0.00001). There was no difference between the two techniques in terms of length of hospital stay (=0.16), operative duration (=0.81), reoperation rate (=0.51), and cost (=0.06).

Conclusions: LSG was demonstrated to have a lower overall complications and a higher weight loss rate, when compared to LGP. Further RCTs of a higher methodological quality level, with a larger sample size, are required in order to validate these findings.