Repeated column chromatography of the n-hexane extract of leaves (Moraceae) led to isolation of a new oleanane triterpene, 3-hydroxy-11-oxo-olean-12-enyl-3-stearate () in addition to three known compounds, taraxerol (), 3-acetoxy-11-methoxy-12-ursene () and 3-acetoxy-11-hydroxy-12-ursene (). Their structures were elucidated by spectroscopic methods and by comparison with data reported in the literatures.
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http://dx.doi.org/10.1080/14786419.2018.1517122 | DOI Listing |
Molecules
December 2024
Ufa Institute of Chemistry, Ufa Federal Research Centre, Russian Academy of Science, 71, Prospect Octyabrya, Ufa 450054, Russia.
Alzheimer's disease (AD) poses a significant public health issue. Despite the fact that today there are several methods of maintenance therapy, one of the most widely used methods is designed to correct the deficiency of acetylcholine. In the search for new potential inhibitors of cholinesterase enzymes, eight new derivatives of 3-oxo- or 2,3-indolo-triterpenic acid conjugated with amino-quinuclidine bicyclic cores were designed and synthesized.
View Article and Find Full Text PDFJ Oral Biosci
December 2024
Faculty of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University, 1-1-1 Tsushima-naka, kita-ku, Okayama, Japan. Electronic address:
Objectives: The bacterium Porphyromonas gingivalis is a major causative agent of periodontitis. In this study, the anti-P. gingivalis compound in bilberry (Vaccinium myrtillus L.
View Article and Find Full Text PDFBMC Genomics
December 2024
The Public Service Platform for Industrialization Development Technology of Marine Biological Medicine and Products of the State Oceanic Administration, Fujian Key Laboratory of Special Marine Bioresource Sustainable Utilization, Southern Institute of Oceanography, Key Laboratory of Developmental and Neural Biology College of Life Sciences, Fujian Normal University, Fuzhou, China.
Background: Cyclocarya paliurus is a high-value tree, and it contains a variety of bioactive secondary metabolites which have broad application prospects in medicine, food and health care. Triterpenoids can improve the bioactive function of C. paliurus health tea and also improve the efficacy of health care tea.
View Article and Find Full Text PDFJ Agric Food Chem
December 2024
Guangdong Engineering Research Center of Biosynthesis and Metabolism of Effective Components of Chinese Medicine, International Institute for Translational Chinese Medicine, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, P. R. China.
Chin Herb Med
October 2024
School of Pharmaceutical Sciences, Jilin University, Changchun 130021, China.
Saponins, the major bioactive components of C. A. Mey.
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