Synthesis and characterization of hybrid Anderson hexamolybdoaluminates(III) functionalized with indometacin or cinnamic acid.

The single-side Al-centred tris-functionalized hybrid organic-inorganic Anderson polyoxomolybdates (CHN)[Al(OH)MoO(OCH)CNH(CHO)]·CHN·4CHOH·5HO (AlMo-NH-Cin; Cin is cinnamic acid, CHO) and (CHN)[Al(OH)MoO(OCH)CNH(CHClNO)]·9HO (AlMo-NH-Indo; Indo is indometacin, CHClNO) have been prepared in a mild three-step synthesis and structurally characterized by single-crystal X-ray diffraction, H NMR and IR spectroscopies and elemental analysis. Both AlMo-NH-Cin and AlMo-NH-Indo crystallize in the orthorhombic space group Pbca. The antibacterial activities of AlMo-NH-Cin and AlMo-NH-Indo against the Gram-negative human mucosal pathogen Moraxella catarrhalis were investigated by determination of the minimum inhibitory concentration, which is 32 µg ml for AlMo-NH-Cin and 256 µg ml for AlMo-NH-Indo.