Immunotherapy and Hyperprogression: Unwanted Outcomes, Unclear Mechanism.

Clin Cancer Res

Laboratory of Molecular Genetics and Immunology, Rockefeller University, New York, New York.

Published: February 2019

Hyperprogression (HP) is a recently defined clinical phenomenon in which patients treated with immunotherapy paradoxically exhibit rapid tumor growth. The mechanisms of hyperprogression remain ill-defined, although recent studies in this issue point to a possible role for Fc receptors in this process..

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359946PMC
http://dx.doi.org/10.1158/1078-0432.CCR-18-3144DOI Listing

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