AI Article Synopsis
- The study explores the use of tramadol as a long-term treatment for patients with opioid dependence, addressing limitations of existing therapies.
- A total of 102 male participants were interviewed, with a mean age of 41.3 years, and 58.8% reported abstaining from other opioids while taking a median tramadol dose of 350 mg/day.
- The findings suggest tramadol could be a viable maintenance option, but more research is needed to compare its effectiveness against other treatments for opioid dependence.
Article Abstract
Background: Certain limitations of the existing opioid substitution therapies necessitate exploration of other options for maintenance of patients with opioid dependence. This study aimed to present the experience of use of tramadol for long-term treatment of patients with opioid dependence.
Methods: This was a cross-sectional interview-based observational study conducted in Uttar Pradesh state in India. Patients with opioid dependence who received oral tramadol treatment for a period of more than 6 months were recruited. Outcome was assessed in terms of self-reported abstinence on tramadol.
Results: A total of 102 participants were recruited in the study, with a mean age of 41.3 years. All the participants were males. Abstinence to extraneous opioids was reported by 58.8% of the sample, and the median dose of tramadol at which abstinence was achieved was 350 mg/d. Those who reported to be taking natural opioids (raw opium or poppy husk) at the time of seeking treatment had higher rates of achieving abstinence.
Conclusions: Tramadol may be a possible option for the maintenance treatment among some opioid-dependent individuals. Further studies are required to establish its efficacy vis-à-vis other medications used in opioid substitution treatment.
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| http://dx.doi.org/10.1080/10826084.2018.1521427 | DOI Listing |
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