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Recent advances in the total synthesis of gracilamine. | LitMetric

Recent advances in the total synthesis of gracilamine.

Chem Commun (Camb)

Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, China.

Published: November 2018

Gracilamine belongs to the Amaryllidaceae alkaloid group and has a unique five-ring skeleton. Its scarcity in plants limits biological studies on it. A number of synthetic chemists have carried out the total synthesis of gracilamine in the past few years. This review will summarize the synthetic studies of gracilamine, and hopes to bring new inspiration to the research of Amaryllidaceae alkaloids.

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Source
http://dx.doi.org/10.1039/c8cc07799aDOI Listing

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