Tartaric Acid and Tartrates in the Synthesis of Bioactive Molecules.

Synthesis (Stuttg)

Department of Chemistry, University of Illinois at Chicago, 845 West Taylor Street, Chicago, Illinois 60607, USA, Fax +1(312)9960431;

Published: January 2001

A review on the syntheses of bioactive compounds published since 1995 using tartaric acid and its derivatives as synthons is presented.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214632PMC
http://dx.doi.org/10.1055/s-2001-15217DOI Listing

Publication Analysis

Top Keywords

tartaric acid
8
acid tartrates
4
tartrates synthesis
4
synthesis bioactive
4
bioactive molecules
4
molecules review
4
review syntheses
4
syntheses bioactive
4
bioactive compounds
4
compounds published
4

Similar Publications

The wilting and yellowing of leafy vegetables caused by spoilage bacteria resulted in serious resource wastage. This study investigated the efficacy of a combined lactic acid (LA) and tartaric acid (TA) treatment against four predominant spoilage bacteria (Erwinia persicina, Citrobacter freundii, Pseudomonas putida, and Pseudomonas punonensis) isolated from spinach and oilseed rape. Detailed analysis using Fourier-transform infrared spectroscopy, flow cytometry, scanning electron microscopy, and light microscopy revealed substantial cellular damage in the bacteria treated by LA and TA, including loss of intracellular material, and collapse of cellular morphology, as well as effective biofilm removal.

View Article and Find Full Text PDF

Citric acid esters of mono- and diglycerides of fatty acids (E 472c) was re-evaluated in 2020 by the Food Additives and Flavourings Panel (FAF Panel) along with acetic acid, lactic acid, tartaric acid, mono- and diacetyltartaric acid, mixed acetic and tartaric acid esters of mono- and diglycerides of fatty acids (E 472a,b,d,e,f). As a follow-up to this assessment, the FAF Panel was requested to assess the safety of citric acid esters of mono- and diglycerides of fatty acids (E 472c) for its use as food additive in food for infants below 16 weeks of age belonging to food categories (FCs) 13.1.

View Article and Find Full Text PDF

In this research, tartaric acid was used to enhance the hydroxyapatite coating on AZ31 Mg alloy substrate through post-treatment and direct addition methods, and the corrosion resistance and biological activity of the samples were investigated. The parameters of concentration, immersion time, and pH of the coating solution were optimized by Electrochemical Impedance Spectroscopy (EIS) and Direct Current (DC) Polarization techniques. According to EIS results in the post-treatment method, tartaric acid with a concentration of 1 g/L, pH = 9 and immersion time of 2 min, increased the corrosion resistance of hydroxyapatite coating from 3630 to about 18,763 Ω.

View Article and Find Full Text PDF

Drug Property Optimization: Design, Synthesis, and Characterization of Novel Pharmaceutical Salts and Cocrystal-Salt of Lumefantrine.

Mol Pharm

January 2025

Department of Industrial and Molecular Pharmaceutics, College of Pharmacy, Purdue University, 575 Stadium Mall Drive, West Lafayette, Indiana 47907, United States.

Lumefantrine (LMF) is a low-solubility antimalarial drug that cures acute, uncomplicated malaria. It exerts its pharmacological effects against erythrocytic stages of spp. and prevents malaria pathogens from producing nucleic acid and protein, thereby eliminating the parasites.

View Article and Find Full Text PDF

Sub-cellular organelle anomalies are frequently observed in diseases such as cancer. Early and precise diagnosis of these alterations can be crucial for patient outcomes. However, current diagnostic tools using conventional organic dyes or metal quantum dots face limitations, including poor biocompatibility, stringent storage conditions, limited solubility in aqueous media, and slow staining speeds.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!