Objective: To examine trends in 12-month postfracture residual disability, nursing home placement, and mortality among patients with a hip fracture between 1990 and 2011.
Design: Secondary analysis of 12-month outcomes from 3 cohort studies and control arms of 2 randomized controlled trials.
Setting: Original studies were conducted as part of the Baltimore Hip Studies (BHS).
Participants: Community-dwelling patients ≥65 years of age hospitalized for surgical repair of a nonpathologic hip fracture (N=988).
Main Outcome Measures: Twelve-month residual disability, mortality, and nursing home residency were examined in case-mix adjusted models by sex and study. Residual disability was calculated by subtracting prefracture scores of Lower Extremity Physical Activities of Daily Living from scores at 12 months postfracture. We also examined the proportion of individuals with a 12-month score higher than their prefracture score (residual disability>0).
Results: Only small improvements were seen in residual disability between 1990 and 2011. No significant differences were seen for men between BHS2 (enrollment 1990-1991; mean residual disability=3.1 activities; 95% confidence interval [CI], 2.16-4.10) and BHS7 (enrollment 2006-2011; mean=3.1 activities; 95% CI, 2.41-3.82). In women, residual disability significantly improved from BHS2 (mean=3.5 activities; 95% CI, 2.95-3.99) to BHS3 (enrollment 1992-1995; mean=2.7 activities; 95% CI, 2.01-3.30) with no significant improvements in later studies. After adjustment, a substantial proportion (91% of men and 79% of women) had a negative outcome (residual disability, died, or nursing home residence at 12 months) in the most recently completed study (BHS7).
Conclusions: Over 2 decades, patients undergoing usual care post-hip fracture still had substantial residual disability. Additional clinical and research efforts are needed to determine how to improve hip fracture treatment, rehabilitation, and subsequent outcomes.
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http://dx.doi.org/10.1016/j.apmr.2018.10.008 | DOI Listing |
Headache
December 2024
IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy.
Objective: To translate and cross-culturally adapt the Headache Disability Inventory (HDI) into Italian and study its reliability and validity.
Methods: A total of 132 participants with primary and secondary headaches were included. The translation was performed following international guidelines with forward and back translation procedures.
Sci Rep
December 2024
Advanced Manufacturing Institute, King Saud University, Riyadh, 11421, Saudi Arabia.
Recently, social demands for a good quality of life have increased among the elderly and disabled people. So, biomedical engineers and robotic researchers aimed to fuse these techniques in a novel rehabilitation system. Moreover, these models utilized the biomedical signals acquired from the human body's particular organ, cells, or tissues.
View Article and Find Full Text PDFExp Neurol
December 2024
Department of Neurology, Brain Research Institute, Niigata University, 1-757 Asahimachi-dori, Chuoku, Niigata 951-8585, Japan. Electronic address:
Background: Despite advances in reperfusion therapies, ischemic stroke remains a major cause of long-term disability due to residual hypoxic lesions persisting after macrovascular reperfusion. These residual hypoxic lesions, caused by microvascular dysfunction, represent an important therapeutic target. We previously demonstrated that oxygen-glucose-deprived peripheral blood mononuclear cells (OGD-PBMCs) migrate to ischemic brain regions and promote functional recovery after stroke.
View Article and Find Full Text PDFArch Orthop Trauma Surg
December 2024
Department of Orthopaedic and Trauma Surgery, Raymond-Poincaré Hospital, APHP, Garches, France.
Purpose: Total knee arthroplasty (TKA) in patients with sequelae of poliomyelitis is a surgical challenge due to muscle weakness, bone deformities or post-polio syndrome (PPS). Few data exist to determine the factors contributing to poor functional results. This study aimed: (1) to describe a cohort of patients with poliomyelitis sequelae who underwent TKA; (2) to examine risk factors for poor functional outcome.
View Article and Find Full Text PDFInt Immunopharmacol
December 2024
Department of Pediatrics, the First Medical Centre, Chinese PLA General Hospital, Beijing, China; Senior Department of Pediatrics, the Seventh Medical Center of PLA General Hospital, Beijing, China; Medical School of Chinese People's Liberation Army, Beijing, China. Electronic address:
Febrile Infection-Related Epilepsy Syndrome (FIRES) is an infrequent yet severe form of epilepsy that rapidly evolves into status epilepticus following a febrile episode. Prompt diagnosis coupled with effective treatment strategies is critical for improving patient outcomes. Herein, we describe the case of an 11-year-old male with FIRES who was successfully treated with tocilizumab, resulting in no further seizures or residual disability.
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