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Mycobacterium tuberculosis complex bacteremia among HIV and non-HIV patients in a Mexican tertiary care center. | LitMetric

AI Article Synopsis

  • The study aimed to identify factors linked to Mycobacterium tuberculosis complex-positive blood cultures among patients diagnosed with tuberculosis from 2000 to 2015.
  • Out of 533 patients, 145 had blood cultures, with 21 testing positive; those with mycobacteremia often had abdominal tuberculosis, low body mass index, and lower hemoglobin and albumin levels.
  • The research highlights the lack of data on mycobacterium bacteremia in HIV-negative individuals, emphasizing the correlation between anemia, hypoalbuminemia, and low BMI with mycobacteremia.

Article Abstract

Objectives: To determine the factors associated with Mycobacterium tuberculosis complex-positive blood culture.

Methods: Case-control study. Sociodemographic, clinical and laboratory data were collected from 2000 to 2015.

Results: We reviewed medical records of 533 patients with culture-proven tuberculosis, of whom 27.2% (145/533) had blood culture available. Patients with mycobacteremia presented more frequently with abdominal tuberculosis, body mass index <18kg/m, and had lower hemoglobin and albumin levels. No differences were observed regarding HIV status.

Conclusions: Few studies have reported on the characteristics associated with Mycobacterium tuberculosis complex bacteremia, especially among Human Immunodeficiency Virus-negative patients. Out of 145 tuberculosis-infected patients with blood culture results available, 21 turned out positive. Anemia, hypoalbuminemia, and a body mass index<18kg/m were associated with mycobacteremia.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427807PMC
http://dx.doi.org/10.1016/j.bjid.2018.10.274DOI Listing

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