The use of X-chromosome short tandem repeats (X-STRs) to solve complex kinship cases has been facilitated by commercial human identification kits, such as the Argus X-12 kit (Qiagen), and the free-access software FamlinkX. For this purpose, allele and haplotype frequencies are required in the populations to be employed. Therefore, we obtained Argus X-12 haplotypes in 933 unrelated males from seven different geographic regions from Mexico. Forensic parameters for individual X-STRs and for three-loci linkage groups are reported. The observed homogeneity between the studied population samples support to use a global Mexican population database (Fst p-value >0.05). In brief, forensic validation of the Argus X-12 kit was performed to facilitate incorporation of X-STRs in forensic casework in this country.
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