We report a case of a 47-year-old woman who presented with a 3-year history of paroxysmal events after suffering traumatic brain injury in a motor vehicle accident. She had not previously been diagnosed with epilepsy. On video-EEG monitoring, she was found to have a right temporal seizure associated with ictal asystole lasting for 18 seconds. Our case raises the possibility that undiagnosed ictal asystole could be a potential cause of sudden unexplained death.
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http://dx.doi.org/10.1080/21646821.2018.1531671 | DOI Listing |
Background: Long QT Syndrome Type-2 (LQT2) is due to loss-of-function variants. encodes K 11.1 that forms a delayed-rectifier potassium channel in the brain and heart.
View Article and Find Full Text PDFJACC Clin Electrophysiol
November 2024
Department of Cardiology, St Vincent's Hospital Melbourne, Fitzroy, VIC, Australia; Faculty of Medicine, Dentistry & Health Sciences, The University of Melbourne, Fitzroy, VIC, Australia; HEART Lab, St Vincent's Institute of Medical Research, Fitzroy, VIC, Australia; HEART Lab, Victor Chang Cardiac Research Institute, Darlinghurst, NSW, Australia. Electronic address: https://twitter.com/pretzeldr.
Epilepsy is an important cause of disability and mortality worldwide. It can be frequently misdiagnosed, and detailed history and relevant investigations are needed to differentiate epilepsy from syncope. Electroencephalogram is a key noninvasive assessment of neurological function, and the diagnostic yield is increased when performed for an extended period in the ambulatory setting with concurrent electrocardiogram and video monitoring.
View Article and Find Full Text PDFUgeskr Laeger
November 2024
Hjerteafdeling Y, Københavns Universitetshospital - Bispebjerg og Frederiksberg Hospital.
Epileptic Disord
December 2024
Division of Neurology, Department of Pediatrics, Montreal Children's Hospital, McGill University Health Centre, Montreal, Quebec, Canada.
Neurology
July 2024
From the Departament de Medicina (L.V.), Universitat Autònoma de Barcelona, Spain; NINDS Center for SUDEP Research (CSR) (L.V., G.C., J.P.H., S.J.O., M.O.-U., B.T., O.M., N.J.H., J.S.H., M.R.S.R., N.L., S.T., R.K.S., D.F., M.N., C.A.S., B.G., S.U.S., R.M.H., B.D., L.M.B., O.D., G.B.R., G.-Q.Z., S.D.L.), McGovern Medical School, University of Texas Health Science Center at Houston; Department of Neurology (L.V.), Hospital del Mar, Barcelona, Spain; Division of Cardiology (C.Y.M.), Department of Pediatrics, Texas Children's Hospital, and Department of Molecular Physiology and Biophysics (C.Y.M.), Baylor College of Medicine, Houston, TX; Department of Neurology (G.C., J.P.H., S.J.O., M.O.-U., B.T., O.M., N.J.H., J.S.H., M.R.S.R., N.L., S.T., G.-Q.Z., S.D.L.), McGovern Medical School, University of Texas Health Science Center at Houston; University of Iowa Carver College of Medicine (R.K.S., B.G., G.B.R.), Iowa City; NYU Langone School of Medicine (D.F., O.D.), New York; Sidney Kimmel Medical College (M.N.), Thomas Jefferson University, Philadelphia, PA; Institute of Neurology (C.A.S., B.D.), University College London, United Kingdom; Department of Neurology (S.U.S.), Feinberg School of Medicine, Northwestern University, Chicago, IL; Department of Neurobiology and the Brain Research Institute (R.M.H.), and Department of Neurobiology (J.A.O.), University of California, Los Angeles; and Cedars-Sinai Medical Center (L.M.B.), Los Angeles, CA.
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