AI Article Synopsis
Article Abstract
Background: Sex-race stratification may lead to identification of risk factors for low antihypertensive medication adherence that are not apparent when assessing risk factors in women and men without race stratification. We examined risk factors associated with low pharmacy refill adherence across sex-race subgroups (white women, black women, white men, black men) within the Cohort Study of Medication Adherence among Older Adults (n = 2,122).
Methods: Pharmacy refill adherence was calculated as proportion of days covered using all antihypertensive prescriptions filled in the year prior to a baseline risk factor survey. Sex- and sex-race-stratified multivariable Poisson regression models with robust standard errors were used to estimate adjusted prevalence ratios and 95% confidence intervals for associations between participant characteristics and low adherence.
Results: Prevalence of low adherence was 22.9% vs. 40.7% in white vs. black women (P < 0.001) and 26.3% vs. 37.2% in white vs. black men (P = 0.003). In multivariable models, reducing antihypertensive medication due to cost was associated with low adherence within each sex-race subgroup. Additional factors associated with low adherence included shorter hypertension duration and comorbidities in white women; not being married and depressive symptoms in white men; and ≥6 primary care visits/year and complementary and alternative medicine use in black men. Among men, not being married and reporting depressive symptoms were associated with low adherence for whites, but not blacks.
Conclusions: Identification of sex-race-specific risk factors for low antihypertensive medication adherence may guide development and implementation of tailored interventions to increase antihypertensive medication adherence and blood pressure control among older patients.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453701 | PMC |
| http://dx.doi.org/10.1016/j.amjms.2018.07.007 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Factors influencing lateral margin diagnosis challenges in Barrett's esophageal cancer: a bicenter retrospective study in Japan.
Clin Endosc
November 2024
Department of Gastroenterology, Sendai Kousei Hospital, Miyagi, Japan.
Background/aims: We aimed to clarify the clinicopathological characteristics and causes of Barrett's esophageal adenocarcinoma (BEA) with unclear demarcation.
Methods: We reviewed BEA cases between January 2010 and August 2022. The lesions were classified into the following two groups: clear demarcation (CD group) and unclear demarcation (UD group).
Post-polypectomy colorectal bleeding: current strategies and the way forward.
Clin Endosc
November 2024
Department of Gastroenterology, Sheffield University Hospitals NHS Trust, Sheffield, United Kingdom.
Post-endoscopic mucosal resection (EMR) bleeding, or clinically significant post-EMR bleeding, is influenced by factors such as polyp size, right-sided colonic lesions, laterally spreading tumors, anticoagulant use, and comorbidities like cardiovascular or chronic renal disease. The optimal prophylactic therapy for post-EMR bleeding remains unknown, with no consensus on specific criteria for its application. Moreover, prophylactic measures, including clipping, suturing, and coagulation, have produced mixed results.
View Article and Find Full Text PDFHealth-related Quality of Life in children and adolescents treated for acute lymphoblastic leukaemia (ALL), compared with healthy peers: a longitudinal study of early survivorship.
J Cancer Surviv
December 2024
Children's Cancer Centre, The Royal Children's Hospital, Melbourne, VIC, Australia.
Purpose: Survival for childhood Acute Lymphoblastic Leukaemia (ALL) has surpassed 90%, making quality of survival an important endpoint in treatment outcomes. This study examined health-related quality of life (HRQoL) trajectories in early survivorship for patients post-ALL treatment compared with a matched group of healthy peers, and explored the association of individual factors (age, sex) and treatment intensity with HRQoL outcomes.
Methods: Eighty-three paediatric patients aged 4-16 years who recently completed treatment for ALL were recruited to the study, alongside 53 age- and sex-matched healthy children.
Agreement between self-reported and objectively measured hypertension diagnosis and control: evidence from a nationally representative sample of community-dwelling middle-aged and older adults in China.
Arch Public Health
December 2024
School of Economics and Finance, Xi'an Jiaotong University, No 74 West Yanta Road, Yanta District, Xi'an, Shaanxi, 710061, PR China.
Background: As the population ages, hypertension has become the leading risk factor for cardiovascular diseases (CVDs) and premature deaths worldwide. Accurate monitoring of CVD risks and planning community-based public health interventions require reliable estimates of hypertension prevalence and management. While the validity of self-reporting in assessing hypertension prevalence has been debated, the concordance between self-reports and clinical measurements of hypertension control remains underexplored, particularly in large, community-based older populations.
View Article and Find Full Text PDFThe relationship between body mass index changes and mortality in geriatric peritoneal dialysis patients: a case-control study.
BMC Nephrol
December 2024
Faculty of Medicine, Department of Internal Medicine, Division of Nephrology, Dokuz Eylul University, Izmir, Turkey.
Background: The prevalence of chronic kidney disease (CKD) is increasing, reflecting the rising incidence of chronic diseases. With the continuous growth of the global geriatric population, a significant portion of individuals with CKD consists of those aged over 65. Regardless of the chosen treatment method, protein-energy loss in patients undergoing renal replacement therapy (RRT) has been associated with elevated morbidity and mortality rates.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!