Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/cyto.a.23638 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Keystone engineers profoundly influence microbial communities by altering their shared environment, often by modifying key resources. Here, we show that in an antibiotic-treated microbial community, bacterial spread is controlled by keystone engineering affecting dispersal- an effect hidden in well-mixed environments. Focusing on two pathogens, non-motile Klebsiella pneumoniae and motile Pseudomonas aeruginosa, we found that both tolerate a β-lactam antibiotic, with Pseudomonas being more resilient and dominating in well-mixed cultures.
View Article and Find Full Text PDFSelecting a smartwatch for trials involving older adults with neurodegenerative diseases: A researcher's framework to avoid hidden pitfalls.
J Biomed Inform
January 2025
Centre for Elderly and Nursing Home Medicine, Department of Global Public Health and Primary Care, University of Bergen, Årstadveien 17 5009 Bergen, Norway; Neuro-SysMed, Department of Neurology, Haukeland University Hospital, Jonas vei 65 5021 Bergen, Norway.
Background: Increased prevalence of neurodegenerative diseases complicates care needs for older adults. Sensing technologies, such as smartwatches, are one available solution which can help address the challenges of aging. Knowledge of the possibilities and pitfalls of these sensing technologies is of key importance to researchers when choosing a device for a trial and considering the sustainability of these technologies in real-world settings.
View Article and Find Full Text PDFHidden Threat in Turbid Waters: Quantifying and Modeling the Bioaccumulation and Risks of Particulate Metals to Clams.
Environ Pollut
January 2025
Fujian Provincial Key Laboratory for Coastal Ecology and Environmental Studies, State Key Lab of Marine Environmental Science, College of the Environment and Ecology, Xiamen University, Xiamen, Fujian 361102, China. Electronic address:
A major proportion of metal contaminants in aquatic environments is bound to suspended particulate matter (SPM), yet environmental monitoring typically focuses on dissolved metals, with the filtration step removing SPM. This step may inadvertently hide the potential risks posed by particulate metals. In this study, we used stable isotope tracers to quantify the contributions of SPM-bound metals to the bioaccumulation of nickel (Ni), copper (Cu), zinc (Zn), cadmium (Cd), and lead (Pb) in Ruditapes philippinarum, a widely distributed clam crucial to global aquaculture.
View Article and Find Full Text PDFSupramolecular discrimination and diagnosis-guided treatment of intracellular bacteria.
Nat Commun
January 2025
College of Chemistry, Nankai University, Tianjin, China.
Pathogenic intracellular bacteria pose a significant threat to global public health due to the barriers presented by host cells hindering the timely detection of hidden bacteria and the effective delivery of therapeutic agents. To address these challenges, we propose a tandem diagnosis-guided treatment paradigm. A supramolecular sensor array is developed for simple, rapid, accurate, and high-throughput identification of intracellular bacteria.
View Article and Find Full Text PDFBicarbonate Within: A Hidden Modulator of Antibiotic Susceptibility.
Antibiotics (Basel)
January 2025
Departments of Medicine and Medical Microbiology & Immunology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA.
Since its standardization, clinical antimicrobial susceptibility testing (AST) has relied upon a standard medium, Mueller-Hinton Broth/Agar (MHB/A), to determine antibiotic resistance. However, this microbiologic medium bears little resemblance to the host milieu, calling into question the physiological relevance of resistance phenotypes it reveals. Recent studies investigating antimicrobial susceptibility in mammalian cell culture media, a more host-mimicking environment, demonstrate that exposure to host factors significantly alters susceptibility profiles.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!