Localizing the sources of stimuli is essential. Most organisms cannot eat, mate, or escape without knowing where the relevant stimuli originate. For many, if not most, animals, olfaction plays an essential role in search. While microorganismal chemotaxis is relatively well understood, in larger animals the algorithms and mechanisms of olfactory search remain mysterious. In this symposium, we will present recent advances in our understanding of olfactory search in flies and rodents. Despite their different sizes and behaviors, both species must solve similar problems, including meeting the challenges of turbulent airflow, sampling the environment to optimize olfactory information, and incorporating odor information into broader navigational systems.
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http://dx.doi.org/10.1523/JNEUROSCI.1668-18.2018 | DOI Listing |
Plants (Basel)
December 2024
Key Laboratory Biological Crop Pathogens & Insects Zhejiang Pro, State Key Laboratory Rice Biology, Institute Insect Science, Zhejiang University, Hangzhou 310058, China.
The flea-weevil Korotyaev (Coleoptera: Curculionidae) is an Eastern Palaearctic Steppe species, and a serious pest of elm trees ( spp., Ulmaceae) by feeding on the leaves (adults) or mining them heavily (larvae) in Xinjiang, China. In order to search for chemical and ecological pest management practices, the olfactory preferences of for leaves of three elm species were investigated.
View Article and Find Full Text PDFCochrane Database Syst Rev
January 2025
Department of Otorhinolaryngology, Amsterdam University Medical Centre, Amsterdam, Netherlands.
Background: NSAID-exacerbated respiratory disease (N-ERD) is a hypersensitivity to non-steroidal anti-inflammatory drugs (NSAIDs), such as aspirin or ibuprofen, accompanied by chronic rhinosinusitis (with or without nasal polyps) or asthma. The prevalence of hypersensitivity to NSAIDs is estimated to be 2%. The first line of treatment is the avoidance of NSAIDs.
View Article and Find Full Text PDFSensors (Basel)
December 2024
Department of Computer Science, Louisiana Tech University, 201 Mayfield Ave, Ruston, LA 71272, USA.
Odor source localization (OSL) technology allows autonomous agents like mobile robots to localize a target odor source in an unknown environment. This is achieved by an OSL navigation algorithm that processes an agent's sensor readings to calculate action commands to guide the robot to locate the odor source. Compared to traditional 'olfaction-only' OSL algorithms, our proposed OSL algorithm integrates vision and olfaction sensor modalities to localize odor sources even if olfaction sensing is disrupted by non-unidirectional airflow or vision sensing is impaired by environmental complexities.
View Article and Find Full Text PDFNeurosci Biobehav Rev
December 2024
Department of Neuroscience, Istituto Superiore di Sanità, Viale Regina Elena 299, Rome 00161, Italy.
A hallmark event in neurodegenerative diseases is represented by the misfolding, aggregation and accumulation of proteins, leading to cellular and network dysfunction preceding the development of clinical symptoms by years. Early diagnosis represents a crucial issue in the field of neuroscience as it offers the potential to utilize this therapeutic window in the future to manage disease-modifying therapy. Seed amplification assays, including Real-Time Quaking-Induced Conversion (RT-QuIC) and Protein Misfolding Cyclic Amplification (PMCA), have emerged in recent years as innovative techniques developed to detect minute amounts of amyloidogenic proteins.
View Article and Find Full Text PDFJ Diabetes Res
December 2024
Department of Medicine, Faculty of Medicine, University of Málaga, Málaga, Spain.
Olfactory dysfunction and cognitive impairment (CI) have been associated with Type 2 diabetes (T2DM), but the mechanisms underlying this association are broadly unknown. This systematic review tends to investigate the relationship between the onset of olfactory dysfunction and CI in patients with T2DM and to explore the potential role of olfactory dysfunction as an early diagnosis biomarker of CI. We conducted a systematic review consulting PubMed and Scopus.
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