Acoustophoresis, the movement of particles with sound, has evolved as a promising handling tool for micrometer-sized particles. Recent developments in thin film deposition technologies have enabled the reproducible fabrication of thin film piezoelectric materials for miniaturized ultrasound transducers. In this study, we combine both technologies and present the first implementation of a thin film Pb(Zr,Ti)O (PZT) transducer as actuation source for bulk acoustic wave (BAW) acoustophoresis. The design and fabrication process was developed for thin film BAW (TFBAW) devices. High-quality piezoelectric layers were produced using Solmates SMP-800 pulsed laser deposition (PLD) equipment which enables wafer-level batch fabrication. Results from simulations and experiments enabled the characterization of different designs and the prediction of the pressure field inside the TFBAW device. Moreover, the acoustic streaming field was analyzed to determine critical particle diameters for acoustophoresis. Operation conditions were identified for the acoustophoretic unit operations particle concentration and sorting. The TFBAW device was able to generate a high acoustic pressure amplitude of 0.55 MPa at a low peak input voltage of 0.5 V. Overall, this study demonstrates that TFBAW devices have the potential of a miniaturized, predictable and reproducible acoustic particle manipulation at a low voltage for lab-on-a-chip applications.
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http://dx.doi.org/10.1039/c8lc00833g | DOI Listing |
J Liposome Res
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SiteDel Group, Department of Pharmacy, University of Oslo, Blindern, Oslo, Norway.
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January 2025
Department of Physics, Washington State University, Pullman, WA 99163, USA.
This work aims to determine the mechanism of the photomechanical response of poly(Methyl methacrylate) polymer doped with the photo-isomerizable dye Disperse Red 1 using the non-isomerizable dye Disperse Orange 11 as a control to isolate photoisomerization. Samples are free-standing thin films with thickness that is small compared with the optical skin depth to assure uniform illumination and photomechanical response throughout their volume, which differentiates these studies from most others. Polarization-dependent measurements of the photomechanical stress response are used to deconvolute the contributions of angular hole burning, molecular reorientation and photothermal heating.
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Service Pharmacie, Hôpital Universitaire Necker-Enfants Malades, Assistance Publique des Hôpitaux de Paris (AP-HP), 149 Rue de Sèvres, F-75015 Paris, France.
Unlabelled: Orodispersible thin film (ODF) is an innovative dosage form that allows for adjustable dosing and improved patient compliance. It is administered by mouth, where it dissolves, making it suitable for children.
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January 2025
Department of Pharmacology and Toxicology, Faculty of Biosciences, University of Veterinary and Animal Sciences, Lahore 54000, Pakistan.
(1) Background: Surra is a debilitating disease of wild and domestic animals caused by (), resulting in significant mortality and production losses in the affected animals. This study is the first to assess the genetic relationships of in naturally affected buffaloes from Multan district, Pakistan, using ITS-1 primers and evaluating the effects of parasitemia and oxidative stress on DNA damage and hematobiochemical changes in infected buffaloes. (2) Methods: Blood samples were collected from 167 buffaloes using a multi-stage cluster sampling strategy, and trypomastigote identification was performed through microscopy and PCR targeting RoTat 1.
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January 2025
Institute of Nanotechnologies, Electronics and Equipment Engineering, Southern Federal University, 347922 Taganrog, Russia.
One of the challenging problems in the research and development of vibration sensors relates to the formation of Ohmic contacts for the removal of an electrical signal. In some cases, it is proposed to use arrays of carbon nanotubes (CNTs), which can serve as highly elastic electrode materials for vibration sensors. The purpose of this work is to study the effect of a current-collecting layer of CNTs grown over silicon on the properties of a lead zirconate titanate (PZT) film, which is frequently employed in mechanical vibration sensors or energy harvesters.
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