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| http://dx.doi.org/10.11604/pamj.2018.30.138.15295 | DOI Listing |
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Lymphomatoid Papulosis Type E With T-Cell Receptor Gamma Positivity.
Clin Cosmet Investig Dermatol
January 2025
Division of Dermatology, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Lymphomatoid papulosis (LyP) is currently categorized as a primary lymphoproliferative disorder that follows a chronic, recurrent clinical course. The diagnosis of LyP is mainly based on clinical presentation and histopathological correlation. Six subtypes of LyP have been described and recognized, each with different histological features and sometimes distinct clinical presentations.
View Article and Find Full Text PDFEpstein-Barr virus-related lymphoproliferative disorders of the skin.
Dermatol Reports
May 2024
Anatomic Pathology and Cytopathology Unit, G. Pascale Foundation National Cancer Institute IRCCS, Naples, Italy.
Article Synopsis
- - Epstein Barr Virus (EBV) is linked to various cancers, including nasopharyngeal and gastric carcinomas, as well as different types of lymphomas that can range from mild to severe illnesses.
- - The review highlights skin-related disorders associated with EBV, such as EBV-positive mucocutaneous ulcer, lymphomatoid granulomatosis, and several lymphomas including diffuse large B cell lymphoma and plasmablastic lymphoma.
- - Due to the rarity of these skin conditions, a multidisciplinary approach and referrals to specialized care centers are recommended for proper management and treatment.
Lymphomatoid Papulosis Type D in a Mestizo-Ancestry Man.
Am J Dermatopathol
November 2024
Service of Dermatology, Hospital General de México "Dr. Eduardo Liceaga, " S.S./School of Medicine, Universidad Nacional Autónoma de México, Mexico City, Mexico; and.
Article Synopsis
- * Type D LyP is characterized by the presence of abnormal CD8+ and CD30+ lymphocytes, which presents diagnostic challenges due to similarities with more aggressive forms of skin lymphomas.
- * A clinical case of a 22-year-old man with type D LyP demonstrated a favorable prognosis, highlighting the need to share findings related to this condition, especially among mestizo or Latin-American patients, as there are few published cases in this demographic.*
Clinical and Histologic Variants of CD8+ Cutaneous T-Cell Lymphomas.
Cancers (Basel)
September 2024
Department of Dermatology, Yale School of Medicine, New Haven, CT 06510, USA.
Article Synopsis
- The text discusses the classification of Cutaneous T-cell Lymphomas (CTCL), highlighting the prevalence of CD4+ T-helper cell variants and a spectrum of CD8+ variants with various clinical and histological features.
- CD8 and cytotoxic molecules can be identified through immunohistochemical staining, but their presence alone is not enough for diagnosis or determining prognosis.
- The review covers specific CTCL subtypes that express CD8 positivity, including mycosis fungoides, lymphomatoid papulosis, and aggressive forms, underscoring the importance of combining clinical, histologic, and immunohistochemical data for accurate diagnosis and treatment.
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