AI Article Synopsis
- The peripheral primitive neuroectodermal tumor (pPNET) is a rare and dangerous cancer commonly found in children or adolescents, typically affecting areas like the limbs and chest.
- A unique case of an 84-year-old man with a history of pPNET in the scrotal sac is presented, marking it as an unprecedented instance not documented before.
- Diagnostic tools like ultrasound, MRI, and molecular imaging for detecting EWS-FLI1 fusion transcripts play crucial roles in determining the tumor's characteristics and distinguishing pPNETs from similar conditions.
Article Abstract
The peripheral primitive neuroectodermal tumor (pPNET) is a rare malignant tumor originating from neuroectoderm that usually occurs in children or adolescent and is frequently located in the extremities, chest cavity, pelvic cavity and chest wall. We present a rare case of an 84-year-old man with a history of pPNET in the scrotal sac, to our knowledge not previously published in the literature. The presence of a large irreducible mass in the inguinal sac forced to exclude a tumor. Ultrasound and MRI are very useful modalities to assess the location of the mass, its dependency from any organ and the tumoral internal structure. Molecular imaging with the detection of EWS-FLI1 fusion transcripts is useful for the diagnosis and differential diagnosis of Ewing sarcoma/pPNETs.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198772 | PMC |
| http://dx.doi.org/10.1159/000447231 | DOI Listing |
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