The original HTML version of this Article omitted to list Harold Y. Hwang as a corresponding author and incorrectly listed Adrian G. Swartz as a corresponding author. This has been corrected in the HTML version of the Article. The PDF version was correct from the time of publication.
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http://dx.doi.org/10.1038/s41467-018-06960-1 | DOI Listing |
Objective: There is uncertainty about whether early infusion of intravenous amino acids confers clinical benefits in critically ill patients. In this study, we aimed to test the hypothesis that intravenous amino acids could improve 90-day mortality in critically ill patients with normal kidney function.
Design: This is a multicentre, open-label, randomised, parallel-controlled trial.
Sci Rep
January 2025
Department of Animal Physiology, The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, Instytucka 3, Jabłonna, 05-110, Poland.
Since the early discovery of QRFP43, intensive research has been primarily focused on its role in the modulation of food intake. As is widely recognised, the regulation of the body's energy status is a highly complex process involving numerous systems, hormones and neurotransmitters. Among the most important regulators of energy status, alongside the satiety and hunger centre located in the hypothalamus, is the HPT axis, which directly and indirectly affects the regulation of metabolism in all cells of the body.
View Article and Find Full Text PDFBMC Anesthesiol
December 2024
Department of Anesthesiology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Aims: The aim of this study was to explore whether continuous infusion causing lubrication can effectively alleviate pain during male urethral catheterization.
Methods: This prospective, multicenter, double-blinded study included 190 male patients scheduled for urethral catheterization. Patients were randomly allocated into four groups: Group A: the catheter was lubricated with paraffin; Group B: the catheter was lubricated with compound lidocaine gel; Group C: the pump continuously infusing with sterilized water; Group D: the pump continuously infusing with 2% lidocaine.
Drug Saf
December 2024
Immunization Safety Office, Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Background: On June 8, 2021, a new 20-valent pneumococcal conjugate vaccine (PCV20, PREVNAR 20, Pfizer, Inc.) was licensed for use in adults aged ≥ 18 years by the US Food and Drug Administration (FDA).
Objective: To describe reports to the Vaccine Adverse Event Reporting System (VAERS) after administration of the 20-valent pneumococcal conjugate vaccine in adults.
MethodsX
December 2024
Department of Biomedical Sciences for Health, University of Milan, Milan, Italy.
The rising prevalence and incidence of Type 1 Diabetes (T1D) highlights its impact on quality of life, long-term health complications, and the economic burden it poses across socio-economic strata. Effective management of T1D demands robust self-care skills, which are significantly influenced by health literacy (HL) levels; studies have shown that lower HL is associated with poorer health outcomes. This scoping review protocol is designed to identify literature trends and hidden patterns in research assessing HL among individuals with T1D.
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