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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218709 | PMC |
| http://dx.doi.org/10.3238/arztebl.2018.0627 | DOI Listing |
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Cutaneous (CLE) and systemic lupus erythematosus (SLE) are autoimmune diseases with a multifactorial pathogenesis. Ultraviolet radiation (UVR) is the most important trigger of CLE; however, the degree of photosensitivity varies between the clinical subtypes. The expression of matrix metalloproteinases (MMPs)-important enzymes involved in skin turnover and homeostasis-is modulated by UVR.
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