This study presents a convenient synthesis of pyrrolo[1,2- a]quinolines and pyrrolo[2,1- a]isoquinolines with simple quinolines or isoquinolines and Morita-Baylis-Hillman carbonates in the presence of copper acetate. A range of functionalized benzoindolizines could be assembled through an S2'/deprotonation/1,5-electrocyclization/oxidation cascade pathway in a one-step process.
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http://dx.doi.org/10.1021/acs.joc.8b02065 | DOI Listing |
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