A catalytic ring-opening reaction of epoxides by nucleophilic trifluoromethoxylation of trifluoromethyl arylsulfonate has been developed based on the use of a cobalt catalyst. This reaction provides an efficient, simple route for directly construction of a wide range of vicinal trifluoromethoxyhydrins under mild conditions. In addition, this method can convert terminal epoxides into target products with good chemo- and regioselectivity.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/jacs.8b10298 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Cobalt-Catalyzed Trifluoromethoxylation of Epoxides.
J Am Chem Soc
November 2018
State Key Laboratory and Institute of Elemento-Organic Chemistry, College of Chemistry , Nankai University, Tianjin 300071 , China.
A catalytic ring-opening reaction of epoxides by nucleophilic trifluoromethoxylation of trifluoromethyl arylsulfonate has been developed based on the use of a cobalt catalyst. This reaction provides an efficient, simple route for directly construction of a wide range of vicinal trifluoromethoxyhydrins under mild conditions. In addition, this method can convert terminal epoxides into target products with good chemo- and regioselectivity.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!