Background: Unhealthy diet, especially consumption of trans fatty acids (TFAs), is a known risk factor for cardiovascular disease (CVD), a leading cause of death in Austria. In 2009, Austria introduced a law regulating the content of TFAs in foods. The aim of this study was to assess the impact of the TFA regulation on CVD-related outcomes.
Methods: The study evaluated the TFA regulation as an intervention in a natural experiment. Two study periods were assessed: pre-intervention (1995-2009) and post-intervention (2010-14). The study compared the age-standardized death rates per 100 000 population for CVD outcomes with those of a 'synthetic' international comparator population, created from data of OECD countries where TFA regulation has not been implemented, but where the population is otherwise comparable.
Results: There was a continuous decrease in CVD-related mortality throughout the study period in both the synthetic international comparator population, as well as in the adult Austrian population, with no significant change in this trend observed as an effect of TFA regulation.
Conclusions: Whilst the results are counterintuitive, given the established link between TFA consumption and an increased risk of CVD, there are many possible explanations: high prevalence of tobacco smoking, changes in TFA content in foods due to international guidance as opposed to formal regulation and a beneficial impact of TFA regulation on sub-groups of the population that might not be detected with nationally aggregated data. However, reduction in TFAs should still be considered an important part of risk factor reduction for CVD and other non-communicable diseases.
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http://dx.doi.org/10.1093/eurpub/cky147 | DOI Listing |
Eur J Nutr
December 2024
Nutrition Research Division, Bureau of Nutritional Sciences, Health Products and Food Branch, Health Canada, 251 Sir Frederick Banting Driveway, Ottawa, ON, K1A 0K9, Canada.
Purpose: Canada's public health objective is that ≥ 90% of the population consume <1% of total energy (< 1%En) as trans fatty acids (TFA), in line with World Health Organization recommendations. Our study aimed to estimate usual intakes of total TFA, industrially-produced TFA (i-TFA), and naturally occurring TFA (n-TFA) overall and in subgroups of the population before Canada's 2018 prohibition on the use of partially hydrogenated oils (PHO) in foods.
Methods: Data from 1-2 24-h recalls was available for 19,670 participants in the cross-sectional Canadian Community Health Survey (CCHS)-Nutrition 2015.
ACS Appl Mater Interfaces
December 2024
School of Physical and Mathematical Sciences, Nanjing Tech University (NanjingTech), 30 South Puzhu Road, Nanjing 211816, China.
The practical applications of aqueous zinc-ion batteries (AZIBs) are hindered by detrimental effects such as dendrites formation at the Zn metal anode interface and parasitic side reactions induced by HO. Hence, we propose adding amide additives to the Zn sulfate electrolyte (ZSO) to regulate the composition and properties of the electrolytes, thereby stabilizing the Zn anode interface. Different amide molecules containing formamide (FA), acetamide (AA), or trifluoroacetamide (TFA) are discussed.
View Article and Find Full Text PDFCell Metab
January 2025
Molecular and Cell Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, USA; Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA. Electronic address:
Dietary fat drives the pathogenesis of atherosclerotic cardiovascular disease (ASCVD), particularly through circulating cholesterol and triglyceride-rich lipoprotein remnants. Industrially produced trans-unsaturated fatty acids (TFAs) incorporated into food supplies significantly promote ASCVD. However, the molecular trafficking of TFAs responsible for this association is not well understood.
View Article and Find Full Text PDFEnviron Sci Technol
December 2024
Department of Civil and Environmental Engineering, Colorado School of Mines, Golden, Colorado 80401, United States.
Am J Clin Nutr
January 2025
Cardiovascular Research Unit, University of Abuja, and University of Abuja Teaching Hospital, Gwagwalada, Abuja, Nigeria; Department of Internal Medicine, Faculty of Clinical Sciences, University of Abuja, Abuja, Nigeria.
Background: Intake of trans-fatty acids (TFAs) is an established risk factor for cardiovascular disease. In April 2023, Nigeria passed regulations limiting TFA content in foods, fats, and oils, but the current level of TFA exposure in the Nigerian population is unknown.
Objectives: To quantify trans-fatty acid (TFA) biomarkers in dried blood spots from Nigerian adults in the Federal Capital Territory before policy enforcement, establish baseline levels for future evaluations, assess subgroup variations by demographic and socioeconomic factors, and compare TFA levels with data from 30 countries worldwide.
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