A redox-responsive supramolecular nanocarrier was constructed from the self-assembly of spermine modified cyclodextrin and oxaliplatin prodrug. The nanocarrier could preferentially accumulate in polyamine transporter over-expressing HCT116 cells, releasing drugs under a reducing intracellular environment to maximize anticancer treatment.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/c8cc07858k | DOI Listing |
Publication Analysis
Top Keywords
oxaliplatiniv prodrug-based
4
prodrug-based supramolecular
4
supramolecular self-delivery
4
self-delivery nanocarrier
4
nanocarrier targeted
4
targeted colorectal
4
colorectal cancer
4
cancer treatment
4
treatment redox-responsive
4
redox-responsive supramolecular
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!